# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA867991 | B | Inhibition of VEGF165-NRP1 interaction by ELISA | Homo sapiens | 52 | single protein format | Scientific Literature | ||
2. | ALA1101244 | B | Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cells at 100 uM | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
3. | ALA1101245 | B | Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
4. | ALA1101246 | B | Displacement of biotinylated-VEGF-A125 from NRP1 b1 domain by cell-free assay | 1 | single protein format | Scientific Literature | |||
5. | ALA1101247 | B | Displacement of [125I]VEGF-A from human NRP1 expressed in human A549 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA1101248 | B | Displacement of biotinylated-VEGF-A125 from human NRP1 expressed in human DU145 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA1101249 | B | Displacement of biotinylated-VEGF-A125 from human NRP1 expressed in HUVEC | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA1111899 | B | Inhibition of VEGF binding to NRP1 expressed in CHO cells | 1 | cell-based format | Scientific Literature | |||
9. | ALA1111900 | B | Displacement of biotinylated VEGF165 from recombinant NRP1 after 2 hrs by competitive binding assay | 2 | single protein format | Scientific Literature | |||
10. | ALA1111901 | B | Inhibition of biotinylated VEGF165 binding to recombinant NRP1 at 100 uM after 2 hrs by competitive binding assay | 35 | single protein format | Scientific Literature | |||
11. | ALA3225604 | B | Binding affinity to human NRP1 (amino acid residues M1 to K644) at 0.125 to 2 uM by surface plasmon resonance assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA3378159 | B | Inhibition of biotinylated VEGFA165 binding to NRP1 (unknown origin) at 10 uM by chemiluminescent assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
13. | ALA3626192 | B | Binding affinity to NRP1 (unknown origin) assessed as reduction in CRYAB-VEGFA (165) protein interaction | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA3881256 | B | Inhibition of neuropilin-1 in human A549 cells assessed as decrease in cell migration at 10 to 100 uM after 4 hrs by trans-well assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
15. | ALA3881257 | B | Inhibition of neuropilin-1 in human DU145 cells assessed as decrease in cell adhesion to extracellular matrix proteins at 10 to 100 uM after 1.5 hrs by calcein-AM dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
16. | ALA3881258 | B | Inhibition of neuropilin-1 in human ACHN cells assessed as decrease in cell migration at 10 to 100 uM after 4 hrs by trans-well assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
17. | ALA4183433 | B | Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR method | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
18. | ALA4183434 | B | Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells at 200 uM treated every 2 mins by ITC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4183435 | B | Inhibition of biotinylated VEGF-A binding to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells after 2 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4183436 | B | Inhibition of biotinylated VEGF-A binding to human NRP1 expressed in human DU145 cells after 2 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature |