# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1015213 | A | Inhibition of CYP3A1/CYP3A2-catalyzed erythromycin N-demethylase activity in dexamethasone-treated Sprague-Dawley rat liver microsomes by spectrophotometry | Rattus norvegicus | 11 | ALA1152815 | microsome format | Scientific Literature | |
2. | ALA3530295 | A | Activity of rat recombinant CYP3A1 expressed in baculovirus-infected insect cells assessed as enzyme-mediated N-((4-(4-fluorophenyl)-2-oxochroman-7-yl)methyl)-2-((S)-2-hydroxy-2-(trifluoromethyl)butanoyl)hydrazinecarboxamide formation at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH | Rattus norvegicus | 1 | ALA3526019 | cell-based format | Scientific Literature | |
3. | ALA3530299 | A | Activity of rat recombinant CYP3A1 expressed in baculovirus-infected insect cells assessed as enzyme-mediated compound formation treated with setileuton at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH | Rattus norvegicus | 1 | ALA3526019 | cell-based format | Scientific Literature | |
4. | ALA3530304 | A | Activity of rat recombinant CYP3A1 expressed in baculovirus-infected insect cells assessed as enzyme-mediated N-((4-(4-fluorophenyl)-2-oxochroman-7-yl)methyl)-2-((S)-2-hydroxy-2-(trifluoromethyl)butanoyl)hydrazinecarboxamide formation preincubated for 3 mins by Michaelis-Menten equation in presence of NADPH for 10 mins | Rattus norvegicus | 1 | ALA3526019 | cell-based format | Scientific Literature | |
5. | ALA4028580 | A | Inhibition of recombinant rat CYP3A1 expressed in baculosomes expression system using fluorogenic-BOMCC as substrate by fluorescent homogeneous assay | Rattus norvegicus | 1 | ALA4024800 | assay format | Scientific Literature |