| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1908273 | A | Mechanism based inhibition of rat cytochrome P450 CYP3A2 | Rattus norvegicus | 1 | ALA1743341 | single protein format | Scientific Literature | |
| 2. | ALA1908274 | A | Mechanism based inhibition of rat cytochrome P450 CYP3A2 measured by testosterone hydroxylation at positions 2-beta and 6-beta | Rattus norvegicus | 1 | ALA1743341 | single protein format | Scientific Literature | |
| 3. | ALA3528173 | A | Drug metabolism assessed as rat recombinant CYP3A2-mediated sulindac sulfone formation measured per pmol of protein at 500 uM after 90 mins by HPLC analysis | Rattus norvegicus | 1 | ALA3525907 | single protein format | Scientific Literature | |
| 4. | ALA3528179 | A | Drug metabolism assessed as rat recombinant CYP3A2-mediated sulindac sulfone formation measured per pmol of protein at 200 uM after 90 mins by HPLC analysis | Rattus norvegicus | 1 | ALA3525907 | single protein format | Scientific Literature | |
| 5. | ALA3530296 | A | Activity of rat recombinant CYP3A2 expressed in baculovirus-infected insect cells assessed as enzyme-mediated N-((4-(4-fluorophenyl)-2-oxochroman-7-yl)methyl)-2-((S)-2-hydroxy-2-(trifluoromethyl)butanoyl)hydrazinecarboxamide formation at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH | Rattus norvegicus | 1 | ALA3526019 | cell-based format | Scientific Literature | |
| 6. | ALA3530300 | A | Activity of rat recombinant CYP3A2 expressed in baculovirus-infected insect cells assessed as enzyme-mediated compound formation treated with setileuton at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH | Rattus norvegicus | 1 | ALA3526019 | cell-based format | Scientific Literature | |
| 7. | ALA3530305 | A | Activity of rat recombinant CYP3A2 expressed in baculovirus-infected insect cells assessed as enzyme-mediated N-((4-(4-fluorophenyl)-2-oxochroman-7-yl)methyl)-2-((S)-2-hydroxy-2-(trifluoromethyl)butanoyl)hydrazinecarboxamide formation preincubated for 3 mins by Michaelis-Menten equation in presence of NADPH for 10 mins | Rattus norvegicus | 1 | ALA3526019 | cell-based format | Scientific Literature | |
| 8. | ALA4725829 | A | Drug metabolism in male rat liver microsomes assessed as CYP3A2-mediated 2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-4-(methylsulfinyl)-2-(methylthio)pyridin-3-yl)acetamide formation | Rattus norvegicus | 1 | ALA4725230 | microsome format | Scientific Literature | |
| 9. | ALA4725830 | A | Drug metabolism in male rat liver microsomes assessed as CYP3A2-mediated 2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2-(methyl-sulfinyl)-4-(methylthio)pyridin-3-yl)acetamide formation | Rattus norvegicus | 1 | ALA4725230 | microsome format | Scientific Literature | |
| 10. | ALA5118020 | A | Inhibition of CYP3A2-mediated metabolite formation in rat liver microsomes assessed as reduction in N-(1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)pentadecanamide metabolism | Rattus norvegicus | 1 | ALA5113488 | microsome format | Scientific Literature | |
| 11. | ALA5118022 | A | Inhibition of CYP3A2 in rat liver microsomes using midazolam as substrate | Rattus norvegicus | 1 | ALA5113488 | microsome format | Scientific Literature | |
| 12. | ALA5233911 | B | Inhibition of rat CYP3A2 | Rattus norvegicus | 1 | ALA5233221 | single protein format | Scientific Literature | |
| 13. | ALA5233912 | B | Binding affinity to rat CYP3A2 | Rattus norvegicus | 1 | ALA5233221 | single protein format | Scientific Literature |
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