| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA856352 | F | Antiviral activity against guinea pig CMV | Caviid betaherpesvirus 2 | 23 | ALA1149480 | organism-based format | Scientific Literature | |
| 2. | ALA1675578 | F | Antiviral activity against Guinea pig cytomegalovirus (strain 22122; ATCC VR-682) infected in guinea pig lung fibroblast after 6 to 7 days by plaque reduction assay | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 2 | ALA1671855 | organism-based format | Scientific Literature | |
| 3. | ALA1693974 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected guinea pig CCL158 cells assessed as plaque reduction measured after 10 days by plaque reduction assay | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 4. | ALA1693977 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as pregnancy outcome measured as live-born pups at 20 mg/kg, po once at 24 hrs post infection and once 7 days post infection | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 5. | ALA1693978 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as reduction in dam blood viral log10 genome copies/ug of DNA at 20 mg/kg, po once at 24 hrs post infection and once at 7 days post infection (Rvb = 3.22 +/- 0.2 log10 genome copies/ug DNA) | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 6. | ALA1693979 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as reduction in viral DNA level in dam spleen at 20 mg/kg, po once at 24 hrs post infection and once at 7 days post infection relative to dam control | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 7. | ALA1693980 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as reduction in viral DNA level in dam liver at 20 mg/kg, po once at 24 hrs post infection and once at 7 days post infection relative to dam control | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 8. | ALA1693981 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as reduction in viral DNA level in pup spleen at 20 mg/kg, po once at 24 hrs post infection and once at 7 days post infection relative to control pup | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 9. | ALA1693982 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as reduction in viral DNA level in pup liver at 20 mg/kg, po once at 24 hrs post infection and once at 7 days post infection relative to control pup | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 10. | ALA1693983 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as pup spleen containing detectable viral DNA at 20 mg/kg, po once at 24 hrs post infection and once at 7 days post infection (Rvb = 44%) | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 11. | ALA1693984 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as pup liver containing detectable viral DNA at 20 mg/kg, po once at 24 hrs post infection and once at 7 days post infection (Rvb = 73%) | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 12. | ALA1693985 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as increase in pup survival at 20 mg/kg, po once at 24 hrs post infection and once at 7 days post infection | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 13. | ALA1693986 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as reduction in pups with detectable viral DNA at 20 mg/kg, po once at 24 hrs post infection and once at 7 days post infection | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 14. | ALA1693987 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as pregnancy outcome measured as live-born pups at 4 mg/kg, po treatment started at 24 hrs post infection for 5 consecutive days (Rvb = 62.5%) | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 15. | ALA1694128 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as reduction in dam viremia at 4 mg/kg, po qd for 5 days | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 16. | ALA1694129 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as dam liver with detectable viral DNA at 4 mg/kg, po qd for 5 days measured 10 days post infection by real-time PCR (Rvb = 100%) | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 17. | ALA1694130 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as dam liver with detectable viral DNA at 4 mg/kg, po qd for 9 days measured 10 days post infection by real-time PCR (Rvb = 100%) | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 18. | ALA1694131 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as fetus liver with detectable viral DNA at 4 mg/kg, po qd for 5 days measured 10 days post infection by real-time PCR (Rvb = 87%) | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 19. | ALA1694132 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as fetus liver with detectable viral DNA at 4 mg/kg, po qd for 9 days measured 10 days post infection by real-time PCR (Rvb = 87%) | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature | |
| 20. | ALA1694133 | F | Antiviral activity against Guinea pig cytomegalovirus strain 22122 infected in second and third trimesters of pregnant Hartley guinea pig assessed as dam spleen with detectable viral DNA at 4 mg/kg, po qd for 5 days measured 10 days post infection by real-time PCR (Rvb = 100%) | Guinea pig cytomegalovirus (strain 22122 / ATCC VR682) (GPCMV) | 1 | ALA1687836 | organism-based format | Scientific Literature |
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