| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA911143 | B | Inhibition of ChemR23 receptor at 10 uM | Homo sapiens | 1 | ALA1137324 | single protein format | Scientific Literature | |
| 2. | ALA3362288 | B | Agonist activity at human CMKLR1 assessed as melanophore absorbance by summary (Abse5) assay | Homo sapiens | 1 | ALA3351646 | single protein format | Scientific Literature | |
| 3. | ALA3880333 | B | Displacement of [125I]-chemerin from ChemR23 (unknown origin) transfected in mouse BaF3 cells after 3 hrs by scintillation counting method | Homo sapiens | 244 | ALA3879908 | cell-based format | Patent Bioactivity Data | |
| 4. | ALA4037568 | B | Agonist activity at CMKLR1 (unknown origin) | Homo sapiens | 1 | ALA4033786 | single protein format | Scientific Literature | |
| 5. | ALA4037586 | B | Antagonist activity at CMKLR1 (unknown origin) | Homo sapiens | 1 | ALA4033786 | single protein format | Scientific Literature | |
| 6. | ALA4368341 | F | Inhibition of chemR23 in human CAL1 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated for 45 mins followed by chemerin addition | Homo sapiens | 29 | ALA4364337 | cell-based format | Scientific Literature | |
| 7. | ALA4368343 | F | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration | Homo sapiens | 29 | ALA4364337 | cell-based format | Scientific Literature | |
| 8. | ALA4368345 | B | Induction of chemR23 internalization in in human CAL1 cells at 10 uM incubated for 30 mins at 37 degC by flow cytometric analysis | Homo sapiens | 1 | ALA4364337 | cell-based format | Scientific Literature | |
| 9. | ALA4368346 | B | Induction of chemR23 internalization in in human CAL1 cells at 3 uM incubated for 30 mins at 37 degC by flow cytometric analysis | Homo sapiens | 2 | ALA4364337 | cell-based format | Scientific Literature | |
| 10. | ALA4368347 | B | Induction of chemR23 internalization in in human CAL1 cells at 10 uM incubated for 30 mins at 4 degC by flow cytometric analysis | Homo sapiens | 1 | ALA4364337 | cell-based format | Scientific Literature | |
| 11. | ALA4368348 | B | Induction of chemR23 internalization in in human CAL1 cells at 3 uM incubated for 30 mins at 4 degC by flow cytometric analysis | Homo sapiens | 2 | ALA4364337 | cell-based format | Scientific Literature | |
| 12. | ALA4368349 | B | Inhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assay | Homo sapiens | 1 | ALA4364337 | cell-based format | Scientific Literature | |
| 13. | ALA4630477 | B | Antagonist activity at human CMKLR1 expressed in CHOK1 cells assessed as inhibition of chemerin-induced beta arrestin2 recruitment at 500 nM preincubated for 30 mins followed by chemerin stimulation and measured after 90 to 180 mins by pathhunter assay | Homo sapiens | 1 | ALA4627411 | cell-based format | Scientific Literature | |
| 14. | ALA4727805 | F | Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins followed by human chemerin addition by FDSS6000 analysis | Homo sapiens | 41 | ALA4725330 | cell-based format | Scientific Literature | |
| 15. | ALA4727817 | B | Inhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assay | Homo sapiens | 2 | ALA4725330 | cell-based format | Scientific Literature | |
| 16. | ALA4883345 | B | PRESTO-Tango GPCRome screening (CMKLR1) | 1 | ALA4507309 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 17. | ALA5033774 | F | Agonist activity against CMKLR1 (unknown origin) assessed as induction of beta-arrestin 2 recruitment at 10 microM by beta arrestin assay relative to control | Homo sapiens | 1 | ALA5032530 | assay format | Scientific Literature | |
| 18. | ALA5033775 | F | Antagonist activity against CMKLR1 (unknown origin) assessed as inhibition of beta-arrestin 2 recruitment at 10 microM by beta arrestin assay relative to control | Homo sapiens | 1 | ALA5032530 | assay format | Scientific Literature | |
| 19. | ALA5036445 | F | Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assay | Homo sapiens | 9 | ALA5036303 | cell-based format | Scientific Literature | |
| 20. | ALA5036457 | F | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method | Homo sapiens | 9 | ALA5036303 | cell-based format | Scientific Literature |
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