# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA911824 | F | Agonist activity at rat P2Y6 receptor assessed as IP accumulation by SPA | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
2. | ALA929980 | F | Antagonist activity at rat P2Y6 receptor | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
3. | ALA1954471 | F | Antagonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as inhibition of UDP-induced increase in intracellular calcium concentration by spectrofluorimetry | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
4. | ALA1955237 | F | Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluorimetry | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
5. | ALA1955240 | F | Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration at 100 uM by spectrofluorimetry | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
6. | ALA935562 | F | Agonist activity at P2Y6 receptor in Wistar rat microglia assessed as increase in intracellular calcium concentration by ratiometric fura-2 fluorescence method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
7. | ALA935563 | F | Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM after 300 secs by ratiometric fura-2 fluorescence method in presence of U73122 | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
8. | ALA935564 | F | Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM after 600 secs by ratiometric fura-2 fluorescence method in presence of thapsigargin | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
9. | ALA922745 | F | Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM after 600 secs by ratiometric fura-2 fluorescence method in presence of xestospongin C | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
10. | ALA922746 | F | Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM by ratiometric fura-2 fluorescence method in presence of reactive blue 2 | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
11. | ALA922747 | F | Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM in presence of suramin by ratiometric fura-2 fluorescence method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
12. | ALA922748 | F | Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM by ratiometric fura-2 fluorescence method in presence of MRS2578 | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
13. | ALA922749 | B | Effect on P2Y6 receptor-mediated cell motility in Wistar rat microglia assessed as formation of lamellipodia-like membrane ruffles at 100 uM after 5 mins | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
14. | ALA922750 | B | Effect on P2Y6 receptor-mediated cell motility in Wistar rat microglia assessed as formation of lamellipodia-like membrane ruffles at 10 uM after 5 mins | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
15. | ALA922751 | B | Effect on P2Y6 receptor-mediated cell motility in Wistar rat microglia at 100 uM by chemotaxis assay | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
16. | ALA968888 | F | Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization at 100 uM by NOVOstar plate reader | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
17. | ALA968891 | F | Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization by NOVOstar plate reader | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
18. | ALA968895 | F | Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced receptor activation at 100 uM relative to UDP | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
19. | ALA1005023 | F | Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitation spectrofluorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
20. | ALA1005025 | F | Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration at 100 uM by dual-excitation spectrofluorimetric analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature |