# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA909957 | B | Binding affinity to human LRH1 relative to 3-(E-Oct-4-en-4-yl)-1-phenylamino-2-phenyl-cis-bicyclo[3.3.0]oct-2-ene by FRET-based peptide recruitment assay | Homo sapiens | 17 | ALA1137321 | single protein format | Scientific Literature | |
2. | ALA909959 | F | Agonist activity at human LRH1 expressed in CV1 cells assessed as SHP reporter gene transactivation by luciferase assay | Homo sapiens | 1 | ALA1137321 | cell-based format | Scientific Literature | |
3. | ALA909960 | F | Agonist activity at human LRH1 assessed as induction of SHP mRNA expression in human primary hepatocytes at 10 uM | Homo sapiens | 1 | ALA1137321 | cell-based format | Scientific Literature | |
4. | ALA909961 | F | Agonist activity at human LRH1 assessed as induction of SHP mRNA expression in HepG2 cells at 10 uM | Homo sapiens | 1 | ALA1137321 | cell-based format | Scientific Literature | |
5. | ALA909963 | B | Binding affinity to human LRH1 by FRET-based peptide recruitment assay | Homo sapiens | 23 | ALA1137321 | single protein format | Scientific Literature | |
6. | ALA983801 | F | Agonist activity at LRH assessed as receptor-coactivator peptide interaction by FRET assay | 1 | ALA1155854 | assay format | Scientific Literature | ||
7. | ALA974384 | B | Activity at LRH assessed as coactivator peptide interaction with receptor ligand binding domain by FRET assay | 1 | ALA1136905 | single protein format | Scientific Literature | ||
8. | ALA974389 | B | Activity at LRH assessed as coactivator peptide interaction with receptor ligand binding domain by FRET assay relative to standard control | 1 | ALA1136905 | single protein format | Scientific Literature | ||
9. | ALA1767446 | F | Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay | Homo sapiens | 31 | ALA1765026 | assay format | Scientific Literature | |
10. | ALA1767448 | F | Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | Homo sapiens | 46 | ALA1765026 | assay format | Scientific Literature | |
11. | ALA1767453 | B | Agonist activity at human LRH-1 ligand binding domain with Coomassie blue staining by PAGE method | Homo sapiens | 3 | ALA1765026 | single protein format | Scientific Literature | |
12. | ALA1767454 | B | Agonist activity at human LRH-1 ligand binding domain at 100 uM with Coomassie blue staining by PAGE method | Homo sapiens | 1 | ALA1765026 | single protein format | Scientific Literature | |
13. | ALA1767623 | F | Agonist activity human LRH-1 in HEK293 cells assessed as increase in SHP mRNA levels at 10 uM after 24 hrs by RT-qPCR method | Homo sapiens | 4 | ALA1765026 | cell-based format | Scientific Literature | |
14. | ALA1767624 | F | Agonist activity human LRH-1 in HEK293 cells assessed as increase in StAR mRNA levels at 10 uM after 24 hrs by RT-qPCR method | Homo sapiens | 4 | ALA1765026 | cell-based format | Scientific Literature | |
15. | ALA1767625 | F | Agonist activity human LRH-1 in HEK293 cells assessed as increase in MeOx1 mRNA levels at 10 uM after 24 hrs by RT-qPCR method | Homo sapiens | 4 | ALA1765026 | cell-based format | Scientific Literature | |
16. | ALA1767626 | F | Agonist activity human LRH-1 in HEK293 cells assessed as increase in GOS2 mRNA levels at 10 uM after 24 hrs by RT-qPCR method | Homo sapiens | 4 | ALA1765026 | cell-based format | Scientific Literature | |
17. | ALA1961868 | B | Effect on CPF(NR5A2) dependent reporter activity in HEK293 cells at 20 uM | 2 | ALA1961794 | cell-based format | Scientific Literature | ||
18. | ALA2114771 | F | PubChem BioAssay. Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2). (Class of assay: confirmatory) | Homo sapiens | 239 | ALA1201862 | cell-based format | PubChem BioAssays | |
19. | ALA4269661 | B | Agonist activity at recombinant full length human LRH1 expressed in HeLa cells after 24 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 7 | ALA4266014 | cell-based format | Scientific Literature | |
20. | ALA4269662 | B | Agonist activity at recombinant full length human LRH1 expressed in HeLa cells at 30 uM after 24 hrs by dual-glo luciferase reporter gene assay relative to control | Homo sapiens | 7 | ALA4266014 | cell-based format | Scientific Literature |