| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA909958 | B | Binding affinity to human SF1 relative to 3-Hexyl-1-phenylamino-2-phenyl-cis-bicyclo[3.3.0]oct-2-ene1 by FRET-based peptide recruitment assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 2. | ALA909964 | B | Binding affinity to human SF1 by FRET-based peptide recruitment assay | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 3. | ALA2114874 | F | PubChem BioAssay. Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inverse agonists of the Steroidogenic Factor 1 Nuclear Receptor (SF1; NR5A1). (Class of assay: confirmatory) | Homo sapiens | 239 | cell-based format | PubChem BioAssays | ||
| 4. | ALA1961867 | B | Effect on SF1(NR5A1) dependent reporter activity in HEK293 cells at 20 uM | 2 | cell-based format | Scientific Literature | |||
| 5. | ALA924745 | B | Inhibition of GAL4-tagged NR5A1 by luciferase assay | 19 | single protein format | Scientific Literature | |||
| 6. | ALA924746 | B | Inhibition of GAL4-tagged NR5A1 at 100 uM by luciferase assay | 3 | single protein format | Scientific Literature | |||
| 7. | ALA1767443 | F | Inverse agonist activity at SF-1 | 2 | assay format | Scientific Literature | |||
| 8. | ALA1767447 | F | Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay | Homo sapiens | 31 | assay format | Scientific Literature | ||
| 9. | ALA1767449 | F | Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | Homo sapiens | 46 | assay format | Scientific Literature | ||
| 10. | ALA3776839 | B | Inhibition of human SF-1 receptor | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4322388 | B | Agonist activity at recombinant full length SF1 (unknown origin) transfected in human HeLa cells incubated for 24 hrs by renilla luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA4345286 | B | Binding affinity to SF1 LBD (218 to 461 residues) (unknown origin) expressed in Escherichia coli BL21 pLysS measured after overnight incubation by fluorescence polarization assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4345288 | B | Displacement of 6N-FAM from SF1 LBD (218 to 461 residues) (unknown origin) expressed in Escherichia coli BL21 pLysS by competitive binding based fluorescence polarization assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 14. | ALA4345293 | B | Binding affinity to human SF1 LBD (218 to 461 residues) expressed in Escherichia coli BL21 by electrophoretic mobility shift assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA4345294 | B | Inhibition of Gal4-fused human SF1 LBD (198 to 462 residues) expressed in CHO-K1 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5227360 | B | Inhibition of Wnt in human HEK293 cells assessed as reduction in STF expression at 1 to 3 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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