# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA909958 | B | Binding affinity to human SF1 relative to 3-Hexyl-1-phenylamino-2-phenyl-cis-bicyclo[3.3.0]oct-2-ene1 by FRET-based peptide recruitment assay | Homo sapiens | 15 | ALA1137321 | single protein format | Scientific Literature | |
2. | ALA909964 | B | Binding affinity to human SF1 by FRET-based peptide recruitment assay | Homo sapiens | 23 | ALA1137321 | single protein format | Scientific Literature | |
3. | ALA924745 | B | Inhibition of GAL4-tagged NR5A1 by luciferase assay | 19 | ALA1144830 | single protein format | Scientific Literature | ||
4. | ALA924746 | B | Inhibition of GAL4-tagged NR5A1 at 100 uM by luciferase assay | 3 | ALA1144830 | single protein format | Scientific Literature | ||
5. | ALA1767443 | F | Inverse agonist activity at SF-1 | 2 | ALA1765026 | assay format | Scientific Literature | ||
6. | ALA1767447 | F | Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay | Homo sapiens | 31 | ALA1765026 | assay format | Scientific Literature | |
7. | ALA1767449 | F | Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | Homo sapiens | 46 | ALA1765026 | assay format | Scientific Literature | |
8. | ALA1961867 | B | Effect on SF1(NR5A1) dependent reporter activity in HEK293 cells at 20 uM | 2 | ALA1961794 | cell-based format | Scientific Literature | ||
9. | ALA2114874 | F | PubChem BioAssay. Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inverse agonists of the Steroidogenic Factor 1 Nuclear Receptor (SF1; NR5A1). (Class of assay: confirmatory) | Homo sapiens | 239 | ALA1201862 | cell-based format | PubChem BioAssays | |
10. | ALA3776839 | B | Inhibition of human SF-1 receptor | Homo sapiens | 1 | ALA3774309 | single protein format | Scientific Literature | |
11. | ALA4322388 | B | Agonist activity at recombinant full length SF1 (unknown origin) transfected in human HeLa cells incubated for 24 hrs by renilla luciferase reporter gene assay | Homo sapiens | 4 | ALA4321799 | cell-based format | Scientific Literature | |
12. | ALA4345286 | B | Binding affinity to SF1 LBD (218 to 461 residues) (unknown origin) expressed in Escherichia coli BL21 pLysS measured after overnight incubation by fluorescence polarization assay | Homo sapiens | 1 | ALA4342491 | assay format | Scientific Literature | |
13. | ALA4345288 | B | Displacement of 6N-FAM from SF1 LBD (218 to 461 residues) (unknown origin) expressed in Escherichia coli BL21 pLysS by competitive binding based fluorescence polarization assay | Homo sapiens | 8 | ALA4342491 | assay format | Scientific Literature | |
14. | ALA4345293 | B | Binding affinity to human SF1 LBD (218 to 461 residues) expressed in Escherichia coli BL21 by electrophoretic mobility shift assay | Homo sapiens | 2 | ALA4342491 | assay format | Scientific Literature | |
15. | ALA4345294 | B | Inhibition of Gal4-fused human SF1 LBD (198 to 462 residues) expressed in CHO-K1 cells | Homo sapiens | 1 | ALA4342491 | cell-based format | Scientific Literature | |
16. | ALA5227360 | B | Inhibition of Wnt in human HEK293 cells assessed as reduction in STF expression at 1 to 3 uM by Western blot analysis | Homo sapiens | 1 | ALA5226302 | cell-based format | Scientific Literature |