| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA895767 | F | Agonist activity at human TGR5 expressed in CHO cells after 5 hrs by CRE-driven luciferase reporter gene assay relative to lithocholic acid | Homo sapiens | 8 | ALA1148757 | cell-based format | Scientific Literature | |
| 2. | ALA895768 | F | Agonist activity at human TGR5 expressed in CHO cells after 5 hrs by CRE-driven luciferase reporter gene assay | Homo sapiens | 9 | ALA1148757 | cell-based format | Scientific Literature | |
| 3. | ALA895773 | F | Agonist activity at human TGR5 expressed in CHO cells at 125 uM after 5 hrs by CRE-driven luciferase reporter gene assay relative to lithocholic acid | Homo sapiens | 1 | ALA1148757 | cell-based format | Scientific Literature | |
| 4. | ALA901743 | F | Activation of TGR5 expressed in HEK293 cells assessed as elevation of cAMP production at 10 uM relative to control | Homo sapiens | 5 | ALA1138272 | cell-based format | Scientific Literature | |
| 5. | ALA901742 | F | Activation of TGR5 expressed in HEK293 cells assessed as elevation of cAMP production at 100 uM relative to control | Homo sapiens | 1 | ALA1138272 | cell-based format | Scientific Literature | |
| 6. | ALA949256 | F | Agonist activity at human TGR5 expressed in CHO cells by luciferase assay | Homo sapiens | 68 | ALA1144009 | cell-based format | Scientific Literature | |
| 7. | ALA949257 | F | Agonist activity at human TGR5 expressed in CHO cells by luciferase assay relative to lithocholic acid | Homo sapiens | 64 | ALA1144009 | cell-based format | Scientific Literature | |
| 8. | ALA949261 | F | Activity at human TGR5 expressed in CHO cells assessed as induction of cAMP formation | Homo sapiens | 1 | ALA1144009 | cell-based format | Scientific Literature | |
| 9. | ALA949262 | F | Activity at human TGR5 expressed in NCI-H716 cells assessed as induction of cAMP formation | Homo sapiens | 1 | ALA1144009 | cell-based format | Scientific Literature | |
| 10. | ALA949263 | F | Agonist activity at human TGR5 expressed in CHO cells at 316 uM by luciferase assay relative to lithocholic acid | Homo sapiens | 2 | ALA1144009 | cell-based format | Scientific Literature | |
| 11. | ALA1043242 | F | Agonist activity at human TGR5 expressed in CHO cells assessed as increase in CRE-driven gene expression by luciferase reporter gene assay | Homo sapiens | 6 | ALA1154755 | cell-based format | Scientific Literature | |
| 12. | ALA1043244 | F | Agonist activity at human TGR5 expressed in CHO cells assessed as increase in CRE-driven gene expression by luciferase reporter gene assay relative to lithocholic acid | Homo sapiens | 4 | ALA1154755 | cell-based format | Scientific Literature | |
| 13. | ALA1040510 | F | Agonist activity at TGR5 expressed in human U2-OS cells assessed as increase in MRE/CRE-driven gene expression by luciferase reporter gene assay | 3 | ALA1154698 | cell-based format | Scientific Literature | ||
| 14. | ALA1040511 | F | Agonist activity at TGR5 expressed in human U2-OS cells assessed as increase in MRE/CRE-driven gene expression by luciferase reporter gene assay relative to control | 1 | ALA1154698 | cell-based format | Scientific Literature | ||
| 15. | ALA1040516 | F | Agonist activity at human TGR5 expressed in melanophores assessed as melanosome dispersion by melanophore assay | Homo sapiens | 2 | ALA1154698 | assay format | Scientific Literature | |
| 16. | ALA1041788 | F | Agonist activity at TGR5 expressed in CHO cells by CRE-driven luciferase reporter gene assay | 56 | ALA1156761 | cell-based format | Scientific Literature | ||
| 17. | ALA1041789 | F | Agonist activity at TGR5 expressed in CHO cells by CRE-driven luciferase reporter gene assay relative to litocholic acid | 56 | ALA1156761 | cell-based format | Scientific Literature | ||
| 18. | ALA1073135 | F | Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase reporter gene assay | Homo sapiens | 66 | ALA1156896 | cell-based format | Scientific Literature | |
| 19. | ALA1073143 | F | Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase reporter gene assay relative to control | Homo sapiens | 1 | ALA1156896 | cell-based format | Scientific Literature | |
| 20. | ALA1260362 | F | Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP level | Homo sapiens | 31 | ALA1255552 | cell-based format | Scientific Literature |
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