| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA904249 | B | Inhibition of GST-p300 HAT assessed as histone acetylation | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 2. | ALA904259 | B | Activity of GST-p300 HAT assessed as HAT activity at 5 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA904260 | B | Activity of GST-p300 HAT assessed as HAT activity at 21 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA904262 | B | Inhibition of GST-p300 HAT expressed in bacteria assessed as histone acetylation | 1 | assay format | Scientific Literature | |||
| 5. | ALA904261 | B | Inhibition of full length GST-p300 expressed in Sf9 cells assessed as histone acetylation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1798681 | B | Binding affinity to immobilized His6-tagged human full-length KAT3B expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA1798682 | B | Binding affinity to His6-tagged immobilized human KAT3B catalytic domain expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA1798685 | B | Inhibition of His6-tagged human full-length KAT3B expressed in Sf9 cells pre-incubated with acetyl-CoA and histone H4 peptide for 20 mins measured after 15 mins by fluorescent spectrofluorimeter analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA1798686 | B | Inhibition of His6-tagged human KAT3B catalytic domain expressed in Sf9 cells pre-incubated with acetyl-CoA and histone H4 peptide for 20 mins measured after 15 mins by fluorescent spectrofluorimeter analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA1938101 | B | Inhibition of human recombinant His-tagged p300 HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate at 200 uM after 5 mins by scintillation counting | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA1938104 | B | Inhibition of human recombinant His-tagged p300 HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate after 5 mins by scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA1938106 | B | Inhibition of human recombinant His-tagged p300 HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate at >200 uM after 5 mins by scintillation counting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA1798505 | B | Competitive inhibition of p300 HAT | 1 | single protein format | Scientific Literature | |||
| 14. | ALA1006960 | B | Inhibition of recombinant His-tagged HAT p300 expressed in Sf21-Baculovirus system | 1 | assay format | Scientific Literature | |||
| 15. | ALA1006961 | B | Inhibition of HAT p300 | 1 | single protein format | Scientific Literature | |||
| 16. | ALA1006964 | B | Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assay | 6 | assay format | Scientific Literature | |||
| 17. | ALA1025548 | B | Inhibition of recombinant p300 | 10 | single protein format | Scientific Literature | |||
| 18. | ALA1029896 | B | Inhibition of human immunoprecipitated histone acetyltransferase p300 in U937 cell nuclear extracts assessed as remaining enzyme activity at 50 uM | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 19. | ALA1021609 | B | Inhibition of HAT p300 catalytic domain R1627K mutant expressed in Escherichia coli BL21 up to 100 uM by fluorography/autoradiography assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA1021610 | B | Inhibition of HAT p300 catalytic domain G1626A mutant expressed in Escherichia coli BL21 up to 100 uM by fluorography/autoradiography assay | Homo sapiens | 1 | assay format | Scientific Literature |
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