# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3424787 | Binding | Inhibition of P300 (unknown origin) using histone H3/[acetyl-3H]-acetyl coenzyme A as substrate at 100 uM | Homo sapiens | 40 | ALA3421539 | single protein format | Scientific Literature | |
2. | ALA3424788 | Binding | Inhibition of P300 (unknown origin) using histone H3/[acetyl-3H]-acetyl coenzyme A as substrate at 10 uM | Homo sapiens | 1 | ALA3421539 | single protein format | Scientific Literature | |
3. | ALA3424792 | Binding | Inhibition of P300 (unknown origin) using histone H3/[acetyl-3H]-acetyl coenzyme A as substrate | Homo sapiens | 13 | ALA3421539 | single protein format | Scientific Literature | |
4. | ALA3424793 | Binding | Inhibition of P300 in human COS7 cells at 30 uM up to 40 mins by Histac FRET analysis | Homo sapiens | 1 | ALA3421539 | cell-based format | Scientific Literature | |
5. | ALA3424794 | Binding | Binding affinity to human recombinant P300 catalytic domain by SPR analysis | Homo sapiens | 2 | ALA3421539 | single protein format | Scientific Literature | |
6. | ALA3424829 | Binding | Inhibition of recombinant P300 (unknown origin) | Homo sapiens | 1 | ALA3421539 | single protein format | Scientific Literature | |
7. | ALA3424834 | Binding | Noncompetitive inhibition of P300 (unknown origin) using biotinylated H3 as substrate after 15 mins by double reciprocal plot analysis | Homo sapiens | 1 | ALA3421539 | single protein format | Scientific Literature | |
8. | ALA3424835 | Binding | Noncompetitive inhibition of P300 (unknown origin) using acetyl CoA as substrate after 15 mins by double reciprocal plot analysis | Homo sapiens | 1 | ALA3421539 | single protein format | Scientific Literature | |
9. | ALA3424839 | Binding | Inhibition of P300 in human U937 cells assessed as reduction in H4K5 histone acetylation at 100 uM by immunoblotting analysis | Homo sapiens | 1 | ALA3421539 | cell-based format | Scientific Literature | |
10. | ALA3424840 | Binding | Inhibition of P300 in human U937 cells assessed as reduction in H3K9 histone acetylation at 100 uM by immunoblotting analysis | Homo sapiens | 1 | ALA3421539 | cell-based format | Scientific Literature | |
11. | ALA3424841 | Binding | Reversible inhibition of P300 (unknown origin) | Homo sapiens | 1 | ALA3421539 | single protein format | Scientific Literature | |
12. | ALA3626589 | Binding | Binding affinity to human p300 by ITC analysis | Homo sapiens | 1 | ALA3621113 | single protein format | Scientific Literature | |
13. | ALA3626894 | Binding | Inhibition of recombinant human p300 using biotinylated histone H3 (1 to 21 amino acid residues) as substrate at 50 uM preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 28 | ALA3621044 | single protein format | Scientific Literature | |
14. | ALA3626895 | Binding | Inhibition of recombinant human p300 using biotinylated histone H3 (1 to 21 amino acid residues) as substrate preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 13 | ALA3621044 | single protein format | Scientific Literature | |
15. | ALA3738206 | Binding | Inhibition of human recombinant Histone acetyltransferase p300 catalytic domain (1284-1672 residues) using [3H]Acetyl-CoA and histone H3 substrate at 50 uM after 1 hr by liquid scintillation counting | Homo sapiens | 10 | ALA3734689 | single protein format | Scientific Literature | |
16. | ALA3738207 | Binding | Inhibition of human recombinant Histone acetyltransferase p300 catalytic domain (1284-1672 residues) using [3H]Acetyl-CoA and histone H3 substrate at 200 uM after 1 hr by liquid scintillation counting | Homo sapiens | 5 | ALA3734689 | single protein format | Scientific Literature | |
17. | ALA3743457 | Binding | Binding affinity to human p300 assessed as change in melting temperature at 10 uM by differential scanning fluorimetry | Homo sapiens | 1 | ALA3739345 | single protein format | Scientific Literature | |
18. | ALA3773268 | Binding | Binding affinity to biotinylated EP300 (unknown origin) expressed in Escherichia coli at 0.2 to 1 uM by Biolayer Interferometric analysis | Homo sapiens | 2 | ALA3769341 | assay format | Scientific Literature | |
19. | ALA3771508 | Binding | Binding affinity to EP300 (unknown origin) at 100 uM by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 14 | ALA3769355 | single protein format | Scientific Literature | |
20. | ALA3771646 | Binding | Binding affinity to EP300 (unknown origin) at 50 uM by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 1 | ALA3769355 | single protein format | Scientific Literature |