| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA981793 | B | Inhibition of TIE1 at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
| 2. | ALA1061930 | B | Binding constant for TIE1 kinase domain | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
| 3. | ALA1059377 | B | Inhibition of TIE1 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
| 4. | ALA1168128 | B | Inhibition of TIE1 at 1 uM | 6 | ALA1165965 | single protein format | Scientific Literature | ||
| 5. | ALA1175096 | B | Inhibition of TIE1 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
| 6. | ALA1245002 | B | Binding affinity to TIE1 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
| 7. | ALA1826211 | B | Activity of TIE1 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
| 8. | ALA1908714 | B | Binding constant for TIE1 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
| 9. | ALA1944382 | B | Inhibition of TIE1 at 1 uM | 1 | ALA1938300 | single protein format | Scientific Literature | ||
| 10. | ALA1943941 | B | Inhibition of TIE1 at 1 uM | 4 | ALA1938284 | single protein format | Scientific Literature | ||
| 11. | ALA2161430 | B | Inhibition of Tie at 1 uM | 1 | ALA2157860 | single protein format | Scientific Literature | ||
| 12. | ALA2209258 | B | Inhibition of TIE1 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
| 13. | ALA2318775 | B | Binding affinity to TIE1 (unknown origin) at 10 nM after 2 hrs by FRET assay | Homo sapiens | 1 | ALA2311339 | single protein format | Scientific Literature | |
| 14. | ALA2379174 | B | Inhibition of TIE-1 phosphorylation in growth factor-stimulated HUVEC at 3 uM after 24 hrs | Homo sapiens | 1 | ALA2375356 | single protein format | Scientific Literature | |
| 15. | ALA2428865 | B | Competitive binding affinity to TIE1 (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 3 | ALA2424622 | single protein format | Scientific Literature | |
| 16. | ALA3111560 | B | Inhibition of TIE1 (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | ALA3108735 | single protein format | Scientific Literature | |
| 17. | ALA3583144 | B | Inhibition of Tel-fused TIE1 (unknown origin) expressed in mouse BA/F3 cells after 48 hrs by luciferase reporter gene assay in absence of recombinant mouse IL3 | Homo sapiens | 4 | ALA3580662 | cell-based format | Scientific Literature | |
| 18. | ALA4025411 | B | Inhibition of wild-type human partial length TIE1 (T819 to A1138 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
| 19. | ALA4044222 | B | Inhibition of wild-type human partial length TIE1 (T819 to A1138 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | assay format | Scientific Literature | |
| 20. | ALA4047638 | B | Inhibition of wild type human partial length TIE1 (T819 to A1138 residues) expressed in bacterial expression system assessed as residual activity by Kinome scan assay relative to control | Homo sapiens | 1 | ALA4043252 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!