# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1011084 | B | Induction of HSF1-mediated heat-shock protein 72 expression in mouse fibroblast with plasmid EGFP at 2 uM after overnight incubation by micro plate fluorometer | Mus musculus | 1 | assay format | Scientific Literature | ||
2. | ALA1614134 | F | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). (Class of assay: confirmatory) [Related pubchem assays: 2118 (Project Summary), 2098 (Primary HTS)] | Mus musculus | 2,368 | cell-based format | PubChem BioAssays | ||
3. | ALA1738092 | F | PUBCHEM_BIOASSAY: HSF-1 induced GFP reporter and Doxycycline induced RFP reporter Measured in Cell-Based System Using Plate Reader - 2038-03_Inhibitor_DoseNoFile_CherryPick_Activity_Set3. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2118] | Mus musculus | 109 | cell-based format | PubChem BioAssays | ||
4. | ALA1738673 | F | PUBCHEM_BIOASSAY: HSF-1 induced GFP reporter and Doxycycline induced RFP reporter Measured in Cell-Based System Using Plate Reader - 2038-03_Inhibitor_DoseNoFile_CherryPick_Internal-Standard_Set3. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2118] | Mus musculus | 416 | cell-based format | PubChem BioAssays | ||
5. | ALA1738500 | F | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493224] | Mus musculus | 1,949 | cell-based format | PubChem BioAssays | ||
6. | ALA1794386 | F | PUBCHEM_BIOASSAY: HSF-1 induced GFP reporter and Doxycycline induced RFP reporter Measured in Cell-Based System Using Plate Reader - 2038-03_Inhibitor_Dose_CherryPick_Activity_Set4. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2118] | 19 | cell-based format | PubChem BioAssays | |||
7. | ALA1964044 | F | PUBCHEM_BIOASSAY: Quantitative-PCR analysis for transcription inhibition of HSF-1 target gene Hsp90aa Measured in Cell-Based System Using RT-PCR - 2038-08_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) | 1 | cell-based format | PubChem BioAssays | |||
8. | ALA1963938 | F | PUBCHEM_BIOASSAY: Sustained Induction of HSF-1 Measured in Cell-Based System Using Plate Reader - 2038-07_Activator_Dose_CherryPick_Activity. (Class of assay: confirmatory) | 568 | cell-based format | PubChem BioAssays | |||
9. | ALA3295293 | B | Inhibition of HSP1 activity in mouse MEF assessed as reduction of hsp25 promoter activity at 5 to 100 uM after 12 hrs by luciferase reporter gene assay | Mus musculus | 1 | single protein format | Scientific Literature | ||
10. | ALA3295294 | B | Inhibition of HSP1 activity in mouse MEF assessed as reduction of hsp70 promoter activity at 5 to 100 uM after 12 hrs by luciferase reporter gene assay | Mus musculus | 1 | single protein format | Scientific Literature | ||
11. | ALA4192879 | B | Activation of HSF1 in MEF assessed as protection against paclitaxel-induced PARP cleavage at 3 uM pretreated for 1 hr followed by paclitaxel addition measured after 24 hrs by immunoblotting analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
12. | ALA4192880 | B | Activation of HSF1 in MEF assessed as protection against paclitaxel-induced caspase3 cleavage at 3 uM pretreated for 1 hr followed by paclitaxel addition measured after 24 hrs by immunoblotting analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
13. | ALA4192881 | B | Activation of HSF1 in MEF assessed as protection against cisplatin-induced PARP cleavage at 3 uM pretreated for 1 hr followed by cisplatin addition measured after 24 hrs by immunoblotting analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
14. | ALA4192882 | B | Activation of HSF1 in MEF assessed as protection against cisplatin-induced caspase3 cleavage at 3 uM pretreated for 1 hr followed by cisplatin addition measured after 24 hrs by immunoblotting analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
15. | ALA4192883 | B | Activation of HSF1 in MEF assessed as protection against IR-induced PARP cleavage at 3 uM pretreated for 1 hr followed by 10 Gy irradiation measured after 48 hrs by immunoblotting analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
16. | ALA4192884 | B | Activation of HSF1 in MEF assessed as protection against IR-induced caspase3 cleavage at 3 uM pretreated for 1 hr followed by 10 Gy irradiation measured after 48 hrs by immunoblotting analysis | Mus musculus | 2 | cell-based format | Scientific Literature |