| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1025712 | B | Binding affinity to sulfenic acid modified peroxiredoxin human HeLa cells at 10 mM by Western blot | Homo sapiens | 1 | ALA1154543 | cell-based format | Scientific Literature | |
| 2. | ALA4144684 | B | Binding affinity to wild type recombinant human N-terminal 6His-tagged peroxiredoxin-1 expressed in Escherichia coli BL21 after 1 hr by LC-MS/MS analysis | Homo sapiens | 1 | ALA4138286 | assay format | Scientific Literature | |
| 3. | ALA4144697 | B | Binding affinity to peroxiredoxin-1 in human Ramos cell lysate incubated overnight by SDS-PAGE based pull down assay | Homo sapiens | 2 | ALA4138286 | assay format | Scientific Literature | |
| 4. | ALA4144698 | B | Binding affinity to peroxiredoxin-1 in human HeLa cell lysate incubated overnight by SDS-PAGE based pull down assay | Homo sapiens | 2 | ALA4138286 | assay format | Scientific Literature | |
| 5. | ALA4144699 | B | Binding affinity to peroxiredoxin-1 in human Ramos cell lysate incubated overnight by LC-MS/MS based pull down assay | Homo sapiens | 2 | ALA4138286 | assay format | Scientific Literature | |
| 6. | ALA4144700 | B | Binding affinity to peroxiredoxin-1 in human HeLa cell lysate incubated overnight by LC-MS/MS based pull down assay | Homo sapiens | 2 | ALA4138286 | assay format | Scientific Literature | |
| 7. | ALA4144705 | B | Binding affinity to wild type recombinant human N-terminal 6His-tagged peroxiredoxin-1 expressed in Escherichia coli BL21 at 0.625 to 40 uM by immunoblot analysis | Homo sapiens | 2 | ALA4138286 | assay format | Scientific Literature | |
| 8. | ALA4144707 | B | Binding affinity to wild type recombinant human N-terminal 6His-tagged peroxiredoxin-1 expressed in Escherichia coli BL21 up to 200 uM by immunoblot analysis | Homo sapiens | 1 | ALA4138286 | assay format | Scientific Literature | |
| 9. | ALA4144708 | B | Binding affinity to recombinant human N-terminal 6His-tagged peroxiredoxin-1 C173A mutant expressed in Escherichia coli BL21 after 1 hr by LC-MS/MS analysis | Homo sapiens | 1 | ALA4138286 | assay format | Scientific Literature | |
| 10. | ALA4270841 | B | Binding affinity to peroxiredoxin-1 in human Hela cells lysates assessed as protein enrichment by measuring normalized heavy/light ratio at by nano-LC-ESIMS/MS analysis | Homo sapiens | 1 | ALA4270485 | cell-based format | Scientific Literature | |
| 11. | ALA4312921 | B | Activation of PRDX1 in human ACHN cells assessed as reduction in reactive oxygen species level at 25 to 50 nM measured after 24 hrs by Cell-rox reagent-based flow cytometry | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
| 12. | ALA4312934 | B | Induction of PRDX1 nuclear translocation in human ACHN cells at 25 to 50 nM measured after 24 hrs by DAPI staining-based microscopic analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
| 13. | ALA4312935 | B | Binding affinity to full-length human PRDX1 by surface plasmon resonance analysis | Homo sapiens | 2 | ALA4311948 | single protein format | Scientific Literature | |
| 14. | ALA4324157 | B | Inhibition of PRDX1 in human PMA-differentiated LPS-stimulated THP1 cells assessed as reduction in NLRP3 inflammasome activation preincubated for 1 hr followed by addition of ATP and mesured after 1 hr by ELISA | Homo sapiens | 1 | ALA4321841 | assay format | Scientific Literature | |
| 15. | ALA4670315 | B | Binding affinity to peroxiredoxin-1 (unknown origin) assessed as association constant by isothermal titration calorimetry | Homo sapiens | 1 | ALA4665786 | single protein format | Scientific Literature | |
| 16. | ALA4670317 | B | Binding affinity to peroxiredoxin-1 (unknown origin) assessed as change in enthalpy by isothermal titration calorimetry | Homo sapiens | 1 | ALA4665786 | single protein format | Scientific Literature | |
| 17. | ALA5145244 | B | Binding affinity to PRDX1 in human MDA-MB-453 cells measured after 6 hrs by pull-down assay | Homo sapiens | 1 | ALA5143564 | cell-based format | Scientific Literature | |
| 18. | ALA5145298 | B | Binding affinity to PRDX1 in human DOHH-2 cells measured after 6 hrs by pull-down assay | Homo sapiens | 1 | ALA5143564 | cell-based format | Scientific Literature | |
| 19. | ALA5145325 | B | Binding affinity to PRDX1 in human DOHH-2 cells at 10 uM measured after 6 hrs in presence of 100 uM PES by pull-down assay | Homo sapiens | 1 | ALA5143564 | cell-based format | Scientific Literature | |
| 20. | ALA5145342 | B | Binding affinity to PRDX1 in human MDA-MB-453 cells at 10 uM measured after 6 hrs in presence of 100 uM PES by pull-down assay | Homo sapiens | 1 | ALA5143564 | cell-based format | Scientific Literature |
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