| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1007222 | F | Activation of Bax in human HL60 cells assessed as nuclear translocation at 80 uM after 8 hrs by immunostaining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3417877 | B | Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 3. | ALA3420576 | B | Activation of Bax in human HuH7 cells assessed as inhibition of mitochondrial accumulation of fluorescent probe Mitotracker Red after 12 to 72 hrs by spectrophotometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3420577 | B | Activation of Bax in human HuH7 cells assessed as inhibition of mitochondrial accumulation of fluorescent probe Mitotracker Red after 72 hrs by spectrophotometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3420578 | B | Activation of Bax in human HuH7 cells assessed as conformational changes by SDS-PAGE analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3420579 | B | Induction of Bax translocation from cytoplasm to mitochondria in human HuH7 cells at 10 uM after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3420580 | B | Activation of Bax in human HuH7 cells assessed as cyt-C release from mitochondria by MitoTracker Red dye-based immunofluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3420581 | B | Activation of Bax in human HuH7 cells assessed as induction of caspase-3 activation at 10 uM by immunofluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3420582 | B | Activation of Bax in human HuH7 cells assessed as formation of apoptotic nuclei at 10 uM by immunofluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3420583 | B | Activation of Bax mutant in human Jurkat cells assessed as increase in apoptosis rate at 10 uM after 72 hrs by DAPI staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3420584 | B | Activation of Bax in human NB4 cells assessed as increase in apoptosis rate at 10 uM after 12 hrs by DAPI staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3420586 | B | Activation of Bax in human HuH7 cells assessed as effect on mitochondrial membrane potential at 1 to 10 uM after 72 hrs by Mitotracker Red dye-based spectrophotometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3420587 | B | Activation of Bax in human NB4 cells assessed as effect on mitochondrial membrane potential at 1 to 10 uM after 72 hrs by Mitotracker Red dye-based spectrophotometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3420589 | B | Activation of Bax in human SH-SY5Y cells assessed as effect on mitochondrial membrane potential at 1 to 10 uM after 72 hrs by Mitotracker Red dye-based spectrophotometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3420590 | B | Activation of Bax in human HuH7 cells assessed as death cells at 10 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3420591 | B | Activation of Bax in human HuH7 cells assessed as cell growth arrest at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4118633 | B | Binding affinity to BAX in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4366052 | B | Activation of Bax in ER-positive human MCF7 cells assessed as reduction in Bax phosphorylation at Ser184 at 5 uM incubated upto 48 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4366053 | B | Activation of Bax in ER-positive human MCF7 cells assessed as increase in active Bax 6A7 isoform protein level at 5 uM incubated upto 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4366055 | B | Activation of Bax in ER-positive human MCF7 cells assessed as increase in cytosolic cytochrome C level at 5 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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