| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA984522 | B | Inhibition of GCN2 Kin.Dom.2,S808G mutant at 3 uM | Homo sapiens | 1 | ALA1142492 | assay format | Scientific Literature | |
| 2. | ALA993456 | B | Binding affinity to human GCN2 at 10 uM relative to control | Homo sapiens | 17 | ALA1151712 | single protein format | Scientific Literature | |
| 3. | ALA1060248 | B | Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
| 4. | ALA1049979 | B | Binding affinity to GCN2 kinase domain 2 S808G mutant assessed as percentage of kinase remaining bound to the bead at 1 uM by T7 phage display based binding assay | Homo sapiens | 1 | ALA1154183 | assay format | Scientific Literature | |
| 5. | ALA1053744 | B | Inhibition of GCN2 kinase domain-2 S808G mutant assessed as enzyme activity at 1 uM relative to untreated control | Homo sapiens | 1 | ALA1155237 | assay format | Scientific Literature | |
| 6. | ALA1169248 | B | Inhibition of GCN2 domian 2 S808G mutant at 1 uM | Homo sapiens | 10 | ALA1165965 | assay format | Scientific Literature | |
| 7. | ALA1174439 | B | Inhibition of GCN2 Domain2 S808G mutant at 10 uM | Homo sapiens | 2 | ALA1177794 | assay format | Scientific Literature | |
| 8. | ALA1244855 | B | Binding affinity to GCN2 Kin.Dom.2, S808G mutant | Homo sapiens | 7 | ALA1240346 | assay format | Scientific Literature | |
| 9. | ALA1826946 | B | Activity of GCN2 Kin.Dom.2, S808G mutant kinase at 1 uM | Homo sapiens | 1 | ALA1821651 | assay format | Scientific Literature | |
| 10. | ALA1908507 | B | Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
| 11. | ALA1942480 | B | Inhibition of human GCN2 domain2 in HL-60 cells lysate assessed as reduction of labeling of acyl-phosphate ATP probe at 100 nM | Homo sapiens | 4 | ALA1938230 | cell-based format | Scientific Literature | |
| 12. | ALA2211493 | B | Inhibition of EIF2AK4 | 1 | ALA2203257 | single protein format | Scientific Literature | ||
| 13. | ALA2213534 | B | Inhibition of GCN2 domain 2 S808G mutant assessed as residual activity at 10 uM relative to control | Homo sapiens | 1 | ALA2203081 | assay format | Scientific Literature | |
| 14. | ALA2342049 | B | Inhibition of GCN2 (unknown origin) assessed as residual activity at 100 nM after 1 hr by competitive binding assay relative to control | Homo sapiens | 1 | ALA2331320 | single protein format | Scientific Literature | |
| 15. | ALA2424033 | B | Inhibition of GCN2 in human PC3 cell lysates at 10 uM using desthiobiotin-tagged ATP probe AX9989 followed by trypsinization by LC/MS analysis | Homo sapiens | 12 | ALA2417377 | single protein format | Scientific Literature | |
| 16. | ALA2424252 | B | Inhibition of GCN2 in human PC3 cell lysates at 30 uM using desthiobiotin-tagged ATP probe AX9989 followed by trypsinization by LC/MS analysis | Homo sapiens | 4 | ALA2417377 | single protein format | Scientific Literature | |
| 17. | ALA2427141 | B | Competitive binding affinity to GCN2 kinase domain 2 S808G mutant (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 5 | ALA2424622 | assay format | Scientific Literature | |
| 18. | ALA2429312 | B | Binding affinity to GCN2 kinase domain 2 S808G mutant (unknown origin) | Homo sapiens | 1 | ALA2424622 | assay format | Scientific Literature | |
| 19. | ALA2443945 | B | Inhibition of GCN2 (unknown origin) assessed as EIF2AK4 phosphorylation | Homo sapiens | 3 | ALA2440009 | single protein format | Scientific Literature | |
| 20. | ALA3271321 | B | Inhibition of GCN2 (unknown origin) using GFP-elF2a as substrate preincubated with substrate for 20 mins measured after 90 mins by Lanthascreen assay | Homo sapiens | 4 | ALA3259523 | single protein format | Scientific Literature |
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