| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA905357 | B | Inhibition of human DNA polymerase kappa at 200 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 2. | ALA934564 | B | Inhibition of human DNA polymerase kappa | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 3. | ALA972134 | B | Inhibition of human DNA polymerase kappa at 200 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA1023118 | B | Inhibition of human DNA polymerase kappa | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA1023121 | B | Inhibition of human DNA polymerase kappa at 100 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA1794536 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] | 7,413 | assay format | PubChem BioAssays | |||
| 7. | ALA1921592 | B | Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 8. | ALA1921595 | B | Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using bovine deoxyribonuclease 1-treated DNA and dNTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 9. | ALA1919791 | B | Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 mins | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA2013674 | B | Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 11. | ALA2013693 | B | Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate up to 30 uM by Lineweaver-Burk plot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA2013694 | B | Non-competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using poly(dA)/oligo(dT)18 as substrate up to 30 uM by Lineweaver-Burk plot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA2013697 | B | Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate by Dixon plot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA2013698 | B | Non-competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using ploy(dA)/oligo(dT)18 as substrate by Dixon plot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA2013699 | B | Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate assessed as increase in substrate Km at 30 uM by Lineweaver-Burk plot analysis relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA2013700 | B | Ratio of Ki for human DNA polymerase kappa using ploy(dA)/oligo(dT)18 as substrate to Ki for human DNA polymerase kappa using dTTP as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA2339792 | B | Inhibition of human DNA polymerase kappa using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA3132281 | B | Inhibition of C-terminal His-6-tagged human DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 19. | ALA3215035 | F | PubChem BioAssay. qHTS for Inhibitors of Polymerase Kappa: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) | 917 | assay format | PubChem BioAssays | |||
| 20. | ALA3854640 | B | Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition measured after 30 mins in presence of dCTP and dGTP by radioactive gel-based primer extension assay | Homo sapiens | 3 | single protein format | Scientific Literature |
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