# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3807470 | Binding | Inhibition of retinoblastoma protein phosphorylation in human HL60 cells at 0.1 to 1 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA3804789 | cell-based format | Scientific Literature | |
2. | ALA1273687 | Binding | Inhibition of Rb phosphorylation at serine 795 in human A549 cells after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA1268955 | cell-based format | Scientific Literature | |
3. | ALA1273688 | Binding | Inhibition of Rb phosphorylation at serine 807/811 in human A549 cells after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA1268955 | cell-based format | Scientific Literature | |
4. | ALA1767843 | Binding | Inhibition of retinoblastoma protein phosphorylation at Ser249/Thr252, Ser807/811, Ser780, and Ser795 in human MCF7 cells after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA1765057 | cell-based format | Scientific Literature | |
5. | ALA1767844 | Binding | Inhibition of retinoblastoma protein in human MCF7 cells assessed as reduction of CDK4 level at 2.5 to 40 uM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA1765057 | cell-based format | Scientific Literature | |
6. | ALA1767845 | Binding | Inhibition of retinoblastoma protein in human MCF7 cells assessed as reduction of cyclin D1 level at 2.5 to 40 uM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA1765057 | cell-based format | Scientific Literature | |
7. | ALA1767846 | Binding | Inhibition of retinoblastoma protein in human MCF7 cells assessed as reduction of CDK1 level at 2.5 to 40 uM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA1765057 | cell-based format | Scientific Literature | |
8. | ALA1767847 | Binding | Inhibition of retinoblastoma protein in human MCF7 cells assessed as reduction of CDK6 level at 2.5 to 40 uM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA1765057 | cell-based format | Scientific Literature | |
9. | ALA1767899 | Binding | Inhibition of retinoblastoma protein in human MCF7 cells assessed as reduction of cyclin E level at 2.5 to 40 uM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA1765057 | cell-based format | Scientific Literature | |
10. | ALA1767900 | Binding | Inhibition of retinoblastoma protein in human MCF7 cells assessed as reduction of cyclin A level at 2.5 to 40 uM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA1765057 | cell-based format | Scientific Literature | |
11. | ALA1767901 | Binding | Inhibition of retinoblastoma protein in human HT-29 cells assessed as reduction of cyclin A level at 2.5 to 40 uM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA1765057 | cell-based format | Scientific Literature | |
12. | ALA1767902 | Binding | Inhibition of retinoblastoma protein in human HT-29 cells assessed as reduction of CDK4 level at 2.5 to 40 uM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA1765057 | cell-based format | Scientific Literature | |
13. | ALA1011869 | Binding | Inhibition of retinoblastoma susceptibility gene product phosphorylation in human MCF7 cells after 24 hrs | Homo sapiens | 3 | ALA1153424 | cell-based format | Scientific Literature | |
14. | ALA954150 | Binding | Inhibition of retinoblastoma susceptibility gene product phosphorylation in human MCF7 cells after 24 hrs | Homo sapiens | 2 | ALA1150411 | cell-based format | Scientific Literature | |
15. | ALA2445144 | Binding | Dephosphorylation of Rb in human A549 cells assessed as increase in E2F1-HDAC1 interaction at 0.1 uM after 8 hrs by immunoprecipitation and Western blotting analysis | Homo sapiens | 1 | ALA2440054 | cell-based format | Scientific Literature | |
16. | ALA2445145 | Binding | Dephosphorylation of Rb in human A549 cells assessed as increase in Rb-E2F1 interaction at 0.1 uM after 8 hrs by immunoprecipitation and Western blotting analysis | Homo sapiens | 1 | ALA2440054 | cell-based format | Scientific Literature | |
17. | ALA2445146 | Binding | Dephosphorylation of Rb in human A549 cells at 0.1 uM after 6 to 12 hrs by Western blotting analysis | Homo sapiens | 1 | ALA2440054 | cell-based format | Scientific Literature | |
18. | ALA3108020 | Binding | Inhibition of pRb p110 phosphorylation in human HCT116 cells after 48 hrs by Western blotting | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
19. | ALA3107984 | Binding | Inhibition of pRb p110 phosphorylation in human MDA-MB-231 cells after 48 hrs by Western blotting | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
20. | ALA3107985 | Binding | Inhibition of pRb p110 phosphorylation in human HCT116 cells at 5 to 10 uM after 48 hrs by Western blotting relative to unphosphorylated p105 | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature |