# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2066542 | B | Displacement of 5-FAM-conjugated AVP-diPhe-FAM from cIAP2 BIR3 domain after 30 mins by fluorescence polarization-based competition assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA2066544 | B | Displacement of AVPFAK(5-FAM)K (Hid-FAM) from cIAP2 BIR2 domain after 30 mins by fluorescence polarization-based competition assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA2160297 | B | Induction of cIAP2 protein degradation in human MDA-MB-231 cells after 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA2160298 | B | Induction of cIAP2 protein degradation in human MDA-MB-231 cells at 1 to 3 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA2160299 | B | Induction of cIAP2 protein degradation in human MDA-MB-231 cells at 10 to 30 nM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA2160301 | B | Induction of cIAP2 protein degradation in human MDA-MB-231 cells at 1 to 3 nM after 24 hrs by Western blot analysis relative to (5S,8S,10aR)-3-acetyl-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA2160475 | B | Induction of cIAP2 protein degradation in human SKOV3 cells after 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA2160476 | B | Induction of cIAP2 protein degradation in human SKOV3 cells at 1 to 3 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA2160477 | B | Induction of cIAP2 protein degradation in human SKOV3 cells at 10 to 30 nM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA2160479 | B | Induction of cIAP2 protein degradation in human SKOV3 cells at 1 to 3 nM after 24 hrs by Western blot analysis relative to | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA2162882 | B | Binding affinity to human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) assessed as dissociation constant after 2 to 3 hrs by fluorescence polarization assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
12. | ALA2162885 | B | Competitive inhibition of human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
13. | ALA2160289 | B | Binding affinity to BIR3 domain of cIAP2 by fluorescence polarization assay | 12 | single protein format | Scientific Literature | |||
14. | ALA999328 | B | Displacement of fluorescently tagged SMF5 from human cloned cIAP2 BIR3 expressed in Escherichia coli BL21 (DE3) by competitive fluorescence polarization assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
15. | ALA985936 | B | Displacement of fluorescent SM5F peptide from His-tagged human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polarization-based assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
16. | ALA954222 | B | Degradation promoting activity of FLAG tagged cIAP1 expressed in human HT1080 cells after 3 hrs by Western blotting analysis | 3 | cell-based format | Scientific Literature | |||
17. | ALA954870 | B | Binding affinity to human BIR3 domain of cIAP1 by fluorescence polarization assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
18. | ALA954066 | B | Binding affinity to human BIR3 domain of cIAP1 at 150 uM after 30 mins by photoaffinity labeling assay in presence of (S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-butyrylamino)-4-methyl-pentanoic acid methyl ester | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA954067 | B | Binding affinity to human BIR3 domain of cIAP1 by photoaffinity labeling assay in presence of (S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-butyrylamino)-4-methyl-pentanoic acid methyl ester | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA1106518 | B | Binding affinity to cIAP2 BIR3 domain by fluorescence polarization assay | 3 | single protein format | Scientific Literature |