| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1805825 | B | Activity of human NTPDase8 expressed in COS7 cells assessed as amount of inorganic phosphate released using ATP as the substrate at 100 uM after 15 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA1805832 | B | Inhibition of human NTPDase8 expressed in COS7 cells assessed as amount of inorganic phosphate released using ATP as the substrate at 100 uM after 15 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA979124 | B | Inhibition of human NTPDase 8 expressed in COS7 cells at 1mM | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA979125 | B | Inhibition of human NTPDase 8 expressed in COS7 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA1002519 | B | Activity of human NTPDase 8 expressed in human 293T cells assessed as drug hydrolysis at 100 uM after 20 mins relative to ATP | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA1005036 | B | Inhibition of human NTPDase 8 expressed in human 293T cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA2390587 | A | Drug metabolism assessed as human nucleotide triphosphate diphosphohydrolase8-mediated compound hydrolysis at 4.24 mM after 1 hr by HPLC analysis relative to ADP | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 8. | ALA3089668 | B | Inhibition of human NTPDase8 assessed as amount of inorganic phosphate released using ATP as the substrate preincubated at 100 uM for 3 mins before substrate addition after 15 mins by malachite green reagent method | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 9. | ALA3293337 | A | Drug metabolism assessed as human NTPDase-8-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis relative to ATP | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA3293343 | A | Drug metabolism assessed as human NTPDase-8-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3293569 | B | Inhibition of human NTPDase-8 using ATP as substrate assessed as inorganic phosphate release at 100 uM after 15 mins relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 12. | ALA4131387 | B | Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by malachite green reagent-based assay | Homo sapiens | 14 | assay format | Scientific Literature | ||
| 13. | ALA4183885 | B | Inhibition of human NTPDase8 at 100 uM using ATP as substrate preincubated for 3 mins followed by substrate addition measured after 10 mins by malachite green reagent-based assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 14. | ALA4183893 | A | Drug metabolism assessed as human NTPDase8-mediated compound hydrolysis at 100 uM relative to ATP | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 15. | ALA4183918 | B | Activation of human NTPDase8 using ATP as substrate preincubated for 3 mins followed by substrate addition measured after 10 mins by malachite green reagent-based assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4315022 | B | Inhibition of human NTPdase-8 expressed in COS7 cell membranes at 100 uM using ATP as substrate preincubated for 3 mins followed by susbtrate addition and measured after 10 mins by malachite green dye based method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 17. | ALA4405670 | B | Inhibition of human NTPDase 8 expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4668694 | B | Inhibition of NTPDase 8 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by PiColorLock gold reagent based colorimetric assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA4687631 | B | Inhibition of human NTPDase8 expressed in green monkey Cos-7 cells using ATP as substrate preincubated for 3 mins followed by substrate addition by malachite green reagent based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4731677 | B | Inhibition of human NTPDase 8 expressed in human COS7 cells using ATP as substrate at 50 uM incubated for 5 mins followed by substrate addition and measured after 30 mins by capillary electrophoresis method | Homo sapiens | 1 | cell-based format | Scientific Literature |
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