# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3602374 | Functional | Agonist activity at GPR120 (unknown origin) expressed in CHO cells by FLIPR calcium flux assay in presence of 0.1% bovine serum albumin | Homo sapiens | 3 | ALA3600322 | cell-based format | Scientific Literature | |
2. | ALA3791350 | Binding | Agonist activity at human C-terminal YFP-tagged FFA4 receptor expressed in HEK293 cells incubated for 5 mins by BRET based beta-arrestin 2 recruitment assay | Homo sapiens | 18 | ALA3785041 | cell-based format | Scientific Literature | |
3. | ALA3791351 | Binding | Agonist activity at human C-terminal YFP-tagged FFA4 receptor expressed in HEK293 cells incubated for 5 mins by BRET based beta-arrestin 2 recruitment assay relative to TUG-424 | Homo sapiens | 11 | ALA3785041 | cell-based format | Scientific Literature | |
4. | ALA3807107 | Functional | Agonist activity at human GPR120 (unknown origin) expressed in CHO cells by calcium influx assay | Homo sapiens | 4 | ALA3804779 | cell-based format | Scientific Literature | |
5. | ALA3830337 | Functional | Agonist activity at GPR120 (unknown origin) by Fluo-4 AM dye based calcium mobilization assay | Homo sapiens | 1 | ALA3826952 | single protein format | Scientific Literature | |
6. | ALA3830338 | Functional | Agonist activity at GPR120 (unknown origin) up to 100 uM by Fluo-4 AM dye based calcium mobilization assay | Homo sapiens | 1 | ALA3826952 | single protein format | Scientific Literature | |
7. | ALA3362265 | Functional | Antagonist activity at human FFA4 receptor expressed in U2OS cells assessed as inhibition of GSK137647A-induced intracellular calcium level after 24 hrs by FLIPR | Homo sapiens | 1 | ALA3351646 | cell-based format | Scientific Literature | |
8. | ALA3362268 | Binding | Agonist activity at mouse FFA4 receptor in human NCI-H716 cells assessed as GLP-1 secretion | Homo sapiens | 1 | ALA3351646 | cell-based format | Scientific Literature | |
9. | ALA3362269 | Binding | Agonist activity at mouse FFA4 receptor in human NCI-H716 cells assessed as GLP-1 secretion in presence of 4-methyl-N-(9H-xanthen-9-yl)benzenesulfonamide | Homo sapiens | 1 | ALA3351646 | cell-based format | Scientific Literature | |
10. | ALA3364891 | Functional | Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR | Homo sapiens | 40 | ALA3351646 | cell-based format | Scientific Literature | |
11. | ALA3364892 | Functional | Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as maximal calcium mobilization after 24 hrs by FLIPR relative to GSK137647A | Homo sapiens | 21 | ALA3351646 | cell-based format | Scientific Literature | |
12. | ALA3365230 | Binding | Inhibition of human FFA4 receptor expressed in U2OS cells | Homo sapiens | 1 | ALA3351646 | cell-based format | Scientific Literature | |
13. | ALA3365234 | Functional | Antagonist activity at human FFA4 receptor expressed in U2OS cells assessed as inhibition of linoleic acid-induced intracellular calcium level after 24 hrs by FLIPR | Homo sapiens | 1 | ALA3351646 | cell-based format | Scientific Literature | |
14. | ALA999466 | Functional | Agonist activity at human GPR120-G-alpha-16 fusion protein expressed in Flp-in HEK293 cells assessed as effect on intracellular calcium concentration at 10 uM by FLIPR assay relative to alpha-linoleic acid | Homo sapiens | 27 | ALA1140222 | cell-based format | Scientific Literature | |
15. | ALA999468 | Functional | Agonist activity at human GPR120-G-alpha-16 fusion protein expressed in Flp-in HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assay | Homo sapiens | 3 | ALA1140222 | cell-based format | Scientific Literature | |
16. | ALA999470 | Functional | Agonist activity at human GPR120-G-alpha-16 fusion protein expressed in Flp-in HEK293 cells assessed as accumulation of phosphorylated ERK1/2 at 10 to 100 uM by Western blotting | Homo sapiens | 2 | ALA1140222 | cell-based format | Scientific Literature | |
17. | ALA2060785 | Functional | Agonist activity at GPR120 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 5 mins by BRET assay | Homo sapiens | 39 | ALA2057144 | cell-based format | Scientific Literature | |
18. | ALA2060788 | Functional | Agonist activity at GPR120 expressed in Flp-In TREx293 cells by calcium assay | Homo sapiens | 1 | ALA2057144 | cell-based format | Scientific Literature | |
19. | ALA2060797 | Functional | Agonist activity at GPR120 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 5 mins by BRET assay relative to TUG-424 | Homo sapiens | 39 | ALA2057144 | cell-based format | Scientific Literature | |
20. | ALA2166564 | Functional | Agonist activity at GPR120 assessed as stimulation of calcium mobilization relative to TUG20 | 9 | ALA2163258 | assay format | Scientific Literature |