# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA969583 | F | Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assay | Mus musculus | 11 | ALA1138588 | cell-based format | Scientific Literature | |
2. | ALA969584 | B | Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assay | Mus musculus | 10 | ALA1138588 | cell-based format | Scientific Literature | |
3. | ALA1044694 | B | Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assay | Mus musculus | 31 | ALA1156025 | cell-based format | Scientific Literature | |
4. | ALA1049843 | F | Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAG | Mus musculus | 17 | ALA1155261 | cell-based format | Scientific Literature | |
5. | ALA1049844 | F | Ratio of compound IC50 to cyclopamine IC50 for inhibition of SHH in mouse Shh-Light2 cells | Mus musculus | 17 | ALA1155261 | cell-based format | Scientific Literature | |
6. | ALA1101544 | B | Inhibition of SHH in mouse Ptch deffective MEF cells after 30 hrs by Gli-responsive beta-galactosidse reporter gene assay | Mus musculus | 18 | ALA1154349 | cell-based format | Scientific Literature | |
7. | ALA1101545 | F | Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assay | Mus musculus | 14 | ALA1154349 | cell-based format | Scientific Literature | |
8. | ALA1101546 | F | Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assay relative to cyclopamine | Mus musculus | 6 | ALA1154349 | cell-based format | Scientific Literature | |
9. | ALA1101547 | F | Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assay relative to 6 uM cyclopamine | Mus musculus | 7 | ALA1154349 | cell-based format | Scientific Literature | |
10. | ALA1101548 | F | Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assay at 15.6 uM relative to 6 uM cyclopamine | Mus musculus | 1 | ALA1154349 | cell-based format | Scientific Literature | |
11. | ALA1220907 | F | Inhibition of N-palmitoylated Shh in mouse Shh Light2 cells after 30 hrs by firefly luciferase reporter gene assay | Mus musculus | 2 | ALA1212710 | cell-based format | Scientific Literature | |
12. | ALA1220909 | F | Inhibition of N-palmitoylated Shh in mouse Shh Light2 cells at > 30 uM after 30 hrs by firefly luciferase reporter gene assay | Mus musculus | 1 | ALA1212710 | cell-based format | Scientific Literature | |
13. | ALA1220910 | F | Inhibition of N-palmitoylated Shh in mouse Shh Light2 cells at 6.25 uM after 30 hrs by firefly luciferase reporter gene assay | Mus musculus | 1 | ALA1212710 | cell-based format | Scientific Literature | |
14. | ALA1220911 | B | Inhibition of Shh in MEF deficient in ptch1 gene assessed as beta-galactosidase activity at 6.6 uM after 30 mins by luminometry | Mus musculus | 1 | ALA1212710 | single protein format | Scientific Literature | |
15. | ALA1220912 | F | Inhibition of N-palmitoylated Shh in mouse Shh Light2 cells at 6.3 to 50 uM after 30 hrs by firefly luciferase reporter assay in presence of 3.6 uM Smo agonist purmorphamine | Mus musculus | 1 | ALA1212710 | cell-based format | Scientific Literature | |
16. | ALA1220913 | F | Inhibition of N-palmitoylated Shh in mouse Shh Light2 cells at 6.3 to 50 uM after 30 hrs by firefly luciferase reporter assay in presence of 100 nM Smo agonist SAG | Mus musculus | 1 | ALA1212710 | cell-based format | Scientific Literature | |
17. | ALA1220914 | B | Inhibition of N-terminal Shh-induced differentiation in mouse C3H10T1/2 cells assessed as inhibition of alkaline phosphatase induction | Mus musculus | 1 | ALA1212710 | cell-based format | Scientific Literature | |
18. | ALA1220915 | B | Inhibition of N-terminal Shh-induced differentiation in mouse C3H10T1/2 cells assessed as inhibition of alkaline phosphatase induction in presence of 3.6 uM purmorphamine | Mus musculus | 1 | ALA1212710 | cell-based format | Scientific Literature | |
19. | ALA1220925 | B | Inhibition of Shh in MEF deficient in ptch1 gene assessed as beta-galactosidase activity at 1.56 to 25 uM after 30 mins by luminometry | Mus musculus | 1 | ALA1212710 | single protein format | Scientific Literature | |
20. | ALA1226127 | F | Activation of Shh in mouse Shh Light2 cells after 30 hrs by luciferase reporter gene assay | Mus musculus | 1 | ALA1221175 | cell-based format | Scientific Literature |