# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA919515 | B | Inhibition of BCRP expressed in human HEK293 cells assessed as maximal mitoxantrone accumulation at 5 uM relative control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA919516 | B | Inhibition of BCRP expressed in human HEK293 cells assessed as maximal mitoxantrone accumulation at 10 uM relative control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA919517 | B | Inhibition of BCRP expressed in human HEK293 cells assessed as maximal mitoxantrone accumulation at 20 uM relative control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA919518 | B | Inhibition of BCRP expressed in human HEK293 cells assessed as maximal mitoxantrone accumulation | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA915475 | B | Inhibition of BCRP expressed in mitoxantrone-resistant human HCT116 cells assessed as increase in mitoxantrone accumulation at 10 uM after 15 mins | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
6. | ALA915476 | B | Inhibition of BCRP expressed in mitoxantrone-resistant human HCT116 cells assessed as increase in mitoxantrone accumulation at 1 uM after 15 mins | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA892735 | B | Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
8. | ALA892734 | B | Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry relative to GF120918 | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
9. | ALA931162 | B | Inhibition of human BCRP pump mediated [3H]mitoxantrone transport in human Caco-2 cells | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
10. | ALA939282 | B | Inhibition of human BCRP mediated mitoxantrone accumulation in wild type MCF7 cells at 5 uM by flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA939283 | B | Inhibition of human BCRP mediated mitoxantrone accumulation in mitoxantrone resistant MCF7 cells at 5 uM by flow cytometry | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
12. | ALA939284 | B | Inhibition of human BCRP mediated mitoxantrone accumulation in mitoxantrone resistant MCF7 cells at 10 uM by flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA923497 | B | Inhibition of human BCRP mediated [3H]mitoxantrone transport activity in human Caco-2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA923498 | B | Inhibition of human BCRP mediated [3H]mitoxantrone transport activity in human Caco-2 cells at 100 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA939579 | B | Inhibition of BCRP expressed in HEK293 cells assessed as mitoxantrone accumulation at 10 uM by spectrofluorimetry | 5 | cell-based format | Scientific Literature | |||
16. | ALA938574 | B | Inhibition of ABCG2 | 4 | single protein format | Scientific Literature | |||
17. | ALA938579 | B | Inhibition of ABCG2 in human Caco-2 cells assessed as [3H]mithoxatrone accumulation at 100 uM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA974467 | B | Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells by Hoechst 33342 assay using one phase exponential association analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA974468 | B | Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells by Hoechst 33342 assay using linear regression analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA974469 | B | Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells at 5.6 uM by Hoechst 33342 assay | Homo sapiens | 1 | cell-based format | Scientific Literature |