# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1799628 | B | Inhibition of West Nile virus NS2B-NS3 serine protease at 50 uM preincubated for 15 mins before substrate addition measured after 15 mins by fluorimetric analysis | West Nile virus | 14 | single protein format | Scientific Literature | ||
2. | ALA980961 | B | Inhibition of WNV recombinant NS2B-NS3 protease at 10 uM | West Nile virus | 7 | single protein format | Scientific Literature | ||
3. | ALA980962 | B | Inhibition of WNV recombinant NS2B-NS3 protease | West Nile virus | 21 | single protein format | Scientific Literature | ||
4. | ALA1034432 | B | Inhibition of WNV NS2B-NS3 protease by enzymatic assay | West Nile virus | 2 | single protein format | Scientific Literature | ||
5. | ALA1034433 | B | Inhibition of WNV NS2B-NS3 protease by tryptophan fluorescence assay | West Nile virus | 2 | single protein format | Scientific Literature | ||
6. | ALA1034434 | B | Binding affinity to WNV NS2B(K96A)-NS3 protease measured as change of 15N chemical shift of Ala36 by NMR spectroscopy | West Nile virus | 1 | single protein format | Scientific Literature | ||
7. | ALA1034435 | B | Binding affinity to WNV NS2B(K96A)-NS3 protease measured as change of 15N chemical shift of Val100 by NMR spectroscopy | West Nile virus | 1 | single protein format | Scientific Literature | ||
8. | ALA1034436 | B | Binding affinity to WNV NS2B(K96A)-NS3 protease measured as change of 15N chemical shift of Ser137 by NMR spectroscopy | West Nile virus | 1 | single protein format | Scientific Literature | ||
9. | ALA1034437 | B | Binding affinity to WNV NS2B(K96A)-NS3 protease measured as change of 1H chemical shift of Glu101 by NMR spectroscopy | West Nile virus | 1 | single protein format | Scientific Literature | ||
10. | ALA1034438 | B | Binding affinity to WNV NS2B-NS3 protease measured as change of 1H chemical shift of Thr52 and Glu101 by NMR spectroscopy | West Nile virus | 1 | single protein format | Scientific Literature | ||
11. | ALA1034439 | B | Inhibition of WNV NS2B-NS3 protease | West Nile virus | 7 | single protein format | Scientific Literature | ||
12. | ALA1047162 | B | Inhibition of WNV NS2B-NS3 protease by fluorescence assay | West Nile virus | 32 | single protein format | Scientific Literature | ||
13. | ALA3384588 | B | Inhibition of West Nile virus NS2B-NS3 protease | West Nile virus | 6 | single protein format | Scientific Literature | ||
14. | ALA3384589 | B | Non-competitive inhibition of West Nile virus NS2B-NS3 protease | West Nile virus | 3 | single protein format | Scientific Literature | ||
15. | ALA3389702 | B | Inhibition of West Nile virus serotype 2 NS2B-NS3 protease at 50 uM by homogeneous fluorimetric assay | West Nile virus | 39 | single protein format | Scientific Literature | ||
16. | ALA3390249 | B | Inhibition of West Nile virus serotype 2 NS2B-NS3 protease by homogeneous fluorimetric assay | West Nile virus | 1 | single protein format | Scientific Literature | ||
17. | ALA3371260 | B | Inhibition of West Nile virus NS2B-NS3 protease at 50 uM | West Nile virus | 71 | single protein format | Scientific Literature | ||
18. | ALA3602130 | B | Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate at 50 uM preincubated for 15 mins followed by substrate addition measured for 15 mins by FRET assay relative to control | West Nile virus | 26 | cell-based format | Scientific Literature | ||
19. | ALA3602131 | B | Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate preincubated for 15 mins followed by substrate addition measured for 15 mins by FRET assay | West Nile virus | 19 | cell-based format | Scientific Literature | ||
20. | ALA3602138 | B | Competitive inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate preincubated for 15 mins followed by substrate addition measured for 15 mins by Cheng-Prusoff plot analysis | West Nile virus | 1 | cell-based format | Scientific Literature |