# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1031488 | B | Inhibition of human HSPA1A ATPase activity assessed as residual enzyme activity at 300 uM relative to control | Homo sapiens | 9 | single protein format | Scientific Literature | ||
2. | ALA1031496 | B | Effect on human HSPA1A ATPase activity assessed as fold change in Kcat at 100 uM relative to control | Homo sapiens | 9 | single protein format | Scientific Literature | ||
3. | ALA1031497 | B | Effect on human HSPA1A ATPase activity assessed as fold change in Kcat at 100 uM in presence of J-domain containing Hdj1 co-chaperone relative to control | Homo sapiens | 9 | single protein format | Scientific Literature | ||
4. | ALA1031500 | B | Effect on human HSPA1A ATPase activity assessed as fold change in Kcat at 100 uM presence of J-domain containing yeast Ydj1 co-chaperone relative to control | Homo sapiens | 9 | single protein format | Scientific Literature | ||
5. | ALA1031501 | B | Inhibition of human Hsp70 ATPase activity assessed as reduction of rate of ATP hydrolysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
6. | ALA1614054 | B | PUBCHEM_BIOASSAY: High Throughput Screening Assay for Hsp70 Inhibitors. (Class of assay: confirmatory) [Related pubchem assays: 786 ] | Homo sapiens | 33 | single protein format | PubChem BioAssays | ||
7. | ALA1614297 | B | PUBCHEM_BIOASSAY: In Vitro Hsp70 Dose Response Fluorescence Polarization Assay for SAR Study. (Class of assay: confirmatory) [Related pubchem assays: 786, 583 ] | Homo sapiens | 52 | single protein format | PubChem BioAssays | ||
8. | ALA1613765 | F | PUBCHEM_BIOASSAY: Dose response cell-based high-throughput screening assay to identify transcriptional activators of heat shock protein 70 (Hsp70). (Class of assay: confirmatory) | Homo sapiens | ⋯ | cell-based format | PubChem BioAssays | ||
9. | ALA1613848 | B | PUBCHEM_BIOASSAY: TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70. (Class of assay: confirmatory) [Related pubchem assays: 583 ] | Homo sapiens | 33 | single protein format | PubChem BioAssays | ||
10. | ALA4044792 | B | Inhibition of HSPA1A (unknown origin) expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by ATP addition by malachite green dye-based assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
11. | ALA4137439 | A | Induction of heat shock response in human MCF7 cells assessed as increase in HSP72 levels up to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature |