# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1010654 | Binding | Inhibition of cIAP1 | 2 | ALA1152772 | single protein format | Scientific Literature | ||
2. | ALA1025777 | Binding | Displacement of fluorescently tagged SM5F from human cIAP-1 BIR3 expressed in Escherichia coli BL21 cells by fluorescence polarization assay | Homo sapiens | 6 | ALA1151714 | cell-based format | Scientific Literature | |
3. | ALA999327 | Binding | Displacement of fluorescently tagged SMF5 from human cloned cIAP1 BIR3 expressed in Escherichia coli BL21 (DE3) by competitive fluorescence polarization assay | Homo sapiens | 5 | ALA1140231 | assay format | Scientific Literature | |
4. | ALA984306 | Binding | Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrs | Homo sapiens | 14 | ALA1149858 | cell-based format | Scientific Literature | |
5. | ALA984307 | Binding | Inhibition of flag-tagged cIAP1 production in human HT1080 cells assessed as ubiquitinated cIAP1 accumulation in presence of MG132 at 30 uM | Homo sapiens | 2 | ALA1149858 | cell-based format | Scientific Literature | |
6. | ALA985935 | Binding | Displacement of fluorescent SM5F peptide from His-tagged human cIAP1 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polarization-based assay | Homo sapiens | 5 | ALA1143377 | cell-based format | Scientific Literature | |
7. | ALA1106517 | Binding | Binding affinity to cIAP1 BIR3 domain by fluorescence polarization assay | 3 | ALA1157823 | single protein format | Scientific Literature | ||
8. | ALA1248007 | Binding | Displacement of fluorescent SM5F peptide from His-tagged human cIAP1 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polarization-based assay | Homo sapiens | 7 | ALA1240488 | cell-based format | Scientific Literature | |
9. | ALA1777015 | Binding | Competitive inhibition of human cIAP1 BIR3 domain after 2 to 3 hrs by fluorescence polarization assay | Homo sapiens | 16 | ALA1772970 | single protein format | Scientific Literature | |
10. | ALA1777016 | Binding | Binding affinity to human cIAP1 BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assay | Homo sapiens | 16 | ALA1772970 | single protein format | Scientific Literature | |
11. | ALA1777017 | Binding | Competitive inhibition of human cIAP1BIR2-BIR3 domain after 2 to 3 hrs by fluorescence polarization assay | Homo sapiens | 16 | ALA1772970 | single protein format | Scientific Literature | |
12. | ALA1777018 | Binding | Binding affinity to human cIAP1 BIR2-BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assay | Homo sapiens | 16 | ALA1772970 | single protein format | Scientific Literature | |
13. | ALA3388612 | Binding | Inhibition of cIAP1 BIR2-3 (unknown origin) assessed as inhibition of polarization activity using N-His-Tb-cBir2-3(154-352) by fluorescence polarization assay | Homo sapiens | 10 | ALA3351229 | single protein format | Scientific Literature | |
14. | ALA1952922 | Functional | Antagonist activity at GST-tagged BIR3 domain of cIAP1 using AbuRPFK-5FAM after 20 mins by fluorescence polarization assay | 37 | ALA1949628 | assay format | Scientific Literature | ||
15. | ALA1952923 | Functional | Antagonist activity at cIAP1 in human MDA-MB-231 cells assessed as cIAP1 degradation after 1 hr by ELISA | Homo sapiens | 18 | ALA1949628 | cell-based format | Scientific Literature | |
16. | ALA3241790 | Binding | Inhibition of cIAP1 BIR3 domain (unknown origin) by fluorescence polarization assay | Homo sapiens | 41 | ALA3232969 | single protein format | Scientific Literature | |
17. | ALA1958905 | Binding | Displacement of AbuRPF-K(5-Fam)-NH2 from human recombinant His-tagged-cIAP1 BIR3 domain after 3 hrs by fluorescence polarization assay | Homo sapiens | 18 | ALA1955754 | single protein format | Scientific Literature | |
18. | ALA2066541 | Binding | Displacement of 5-FAM-conjugated AVP-diPhe-FAM from cIAP1 BIR3 domain after 30 mins by fluorescence polarization-based competition assay | Homo sapiens | 1 | ALA2062482 | single protein format | Scientific Literature | |
19. | ALA2066543 | Binding | Displacement of AVPFAK(5-FAM)K (Hid-FAM) from cIAP1 BIR2 domain after 30 mins by fluorescence polarization-based competition assay | Homo sapiens | 1 | ALA2062482 | single protein format | Scientific Literature | |
20. | ALA2156772 | Binding | Induction of cIAP1-mediated AR degradation in human MCF7 cells at 30 uM after 24 hrs by Western blot analysis relative to control | Homo sapiens | 2 | ALA2150969 | cell-based format | Scientific Literature |
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