# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1827241 | B | Activity of RIPK1 kinase at 1 uM | 1 | single protein format | Scientific Literature | |||
2. | ALA1908621 | B | Binding constant for RIPK1 kinase domain | 72 | single protein format | Scientific Literature | |||
3. | ALA1943613 | B | Inhibition of human RIPK1 in HL-60 cells lysate assessed as reduction of labeling of acyl-phosphate ATP probe at 100 nM | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA985318 | B | Inhibition of GST-tagged human recombinant RIP1 kinase expressed in Sf9 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA995019 | B | Inhibition of RIPK1 at 3 uM | 1 | single protein format | Scientific Literature | |||
6. | ALA1062869 | B | Binding constant for RIPK1 kinase domain | Homo sapiens | 38 | single protein format | Scientific Literature | ||
7. | ALA1052947 | B | Inhibition of RIPK1 assessed as enzyme activity at 1 uM relative to untreated control | 1 | single protein format | Scientific Literature | |||
8. | ALA1166843 | B | Inhibition of RIPK1 at 1 uM | 10 | single protein format | Scientific Literature | |||
9. | ALA1175253 | B | Inhibition of RIPK1 at 10 uM | 2 | single protein format | Scientific Literature | |||
10. | ALA1221001 | B | Inhibition of human RIP1 K45M mutant autophosphorylation expressed in HEK293T cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
11. | ALA1221002 | B | Inhibition of endogenous RIP1 autophosphorylation in human Jurkat cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA1221004 | B | Inhibition of human RIP1 K45M mutant autophosphorylation expressed in Sf9 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
13. | ALA1221005 | B | Inhibition of human RIP1 K45M mutant autophosphorylation expressed in FADD deficient human Jurkat cells in presence of increasing concentration of ATP | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA1221008 | B | Inhibition of human RIP1 S161E mutant autophosphorylation expressed in HEK293T cells at 100 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA1221012 | B | Inhibition of human RIP1 K45M mutant autophosphorylation expressed in FADD deficient human Jurkat cells at 10 to 30 uM | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
16. | ALA1221013 | B | Inhibition of human RIP1 S161E mutant autophosphorylation expressed in HEK293T cells at 10 to 30 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA1221014 | B | Inhibition of human RIP1 K45M mutant autophosphorylation expressed in Sf9 cells at 10 to 30 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA1244958 | B | Binding affinity to RIPK1 | 7 | single protein format | Scientific Literature | |||
19. | ALA1787148 | B | Binding affinity to human RIPK1 at 10 uM incubated for 1 hr by kinase binding assay relative to untreated control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
20. | ALA1787533 | B | Binding affinity to human RIPK1 incubated for 1 hr by kinase binding assay | Homo sapiens | 1 | single protein format | Scientific Literature |