# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1000349 | B | Activation of large-conductance calcium-activated potassium channel-mediated vasorelaxation in endothelium-denuded normotensive Wistar rat thoracic aorta assessed as potassium chloride-induced contractile tension relative to NS-1619 | Rattus norvegicus | 13 | tissue-based format | Scientific Literature | ||
2. | ALA1000350 | B | Activation of large-conductance calcium-activated potassium channel-mediated vasorelaxation in endothelium-denuded normotensive Wistar rat thoracic aorta assessed as potassium chloride-induced contractile tension | Rattus norvegicus | 18 | single protein format | Scientific Literature | ||
3. | ALA1000351 | B | Activation of large-conductance calcium-activated potassium channel-mediated vasorelaxation in endothelium-denuded normotensive Wistar rat thoracic aorta assessed as potassium chloride-induced contraction in presence of tetraethylammonium chloride | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
4. | ALA1003078 | B | Activation of large-conductance calcium-activated potassium channel-mediated vasorelaxation in endothelium-denuded normotensive Wistar rat thoracic aorta assessed as potassium chloride-induced contraction in presence of iberiotoxin | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
5. | ALA973266 | B | Induction of BK channel mediated vasorelaxation activity in Kcl-induced contraction in Wistar rat aorta | Rattus norvegicus | 27 | tissue-based format | Scientific Literature | ||
6. | ALA973267 | B | Induction of BK channel mediated vasorelaxation activity in Kcl-induced contraction in Wistar rat aorta in presence of IbTX | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
7. | ALA1016925 | B | Activation of BK channel in Wistar rat thoracic aorta assessed as relaxation of KCl-induced contraction | Rattus norvegicus | 19 | tissue-based format | Scientific Literature | ||
8. | ALA1016926 | B | Activation of BK channel in Wistar rat thoracic aorta assessed as relaxation of KCl-induced contraction in presence of potassium channel blocker TEAC | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
9. | ALA959109 | B | Activation of BK channel in rat cerebral myocytes by voltage patch clamp method | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
10. | ALA4838225 | B | Inhibition of rat BK calcium channel expressed in Xenopus laevis oocytes assessed as V1/2 at 10 uM at -80 to 200 mV by patch clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
11. | ALA4838226 | B | Inhibition of rat BK calcium channel expressed in Xenopus laevis oocytes assessed as maximum conductance at 10 uM at -80 to 200 mV by patch clamp assay relative to control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
12. | ALA4838227 | B | Inhibition of rat BK calcium channel expressed in Xenopus laevis oocytes assessed as increase in inward current tail at 10 uM at -80 to 200 mV by patch clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
13. | ALA4838228 | B | Inhibition of rat BK calcium channel expressed in Xenopus laevis oocytes assessed as G-V shift toward more negative voltage at 10 uM at -80 to 200 mV by patch clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
14. | ALA4838229 | B | Inhibition of rat BK calcium channel expressed in Xenopus laevis oocytes assessed as increase in outward current tail at 10 uM at -80 to 200 mV by patch clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
15. | ALA5116752 | B | Agonist activity at rat BK calcium channel alpha expressed in CHO cells assessed as increase in current amplitude at 10 uM by automated whole cell patch clamp analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
16. | ALA5116753 | B | Agonist activity at rat BK calcium channel alpha expressed in CHO cells assessed as fold change in current amplitude at 10 uM by automated whole cell patch clamp analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
17. | ALA5116754 | B | Antagonist activity at rat BK calcium channel alpha expressed in CHO cells assessed as decrease in current amplitude at 10 uM by automated whole cell patch clamp analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
18. | ALA5116755 | B | Agonist activity at rat BK calcium channel alpha expressed in CHO cells assessed as increase in current amplitude at 0.001 to 100 uM in presence of compound 3 by automated whole cell patch clamp analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
19. | ALA5149704 | B | Activation of rat Slo expressed in Xenopus laevis oocytes at 10 uM with 100 mV holding potential by patch-clamp electrophysiological method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
20. | ALA5149705 | B | Activation of rat Slo expressed in Xenopus laevis oocytes assessed as shift in voltage at half activation at 10 uM with 100 mV holding potential by patch-clamp electrophysiological method | Rattus norvegicus | 1 | cell-based format | Scientific Literature |