# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA934562 | B | Inhibition of human DNA polymerase eta at 100 uM | Homo sapiens | 2 | ALA1143937 | single protein format | Scientific Literature | |
2. | ALA973074 | B | Inhibition of human DNA polymerase eta at 200 uM | Homo sapiens | 1 | ALA1157184 | single protein format | Scientific Literature | |
3. | ALA1023120 | B | Inhibition of human DNA polymerase eta | Homo sapiens | 2 | ALA1152764 | single protein format | Scientific Literature | |
4. | ALA1023123 | B | Inhibition of human DNA polymerase eta at 100 uM | Homo sapiens | 2 | ALA1152764 | single protein format | Scientific Literature | |
5. | ALA1794569 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] | 18,965 | ALA1201862 | assay format | PubChem BioAssays | ||
6. | ALA1919789 | B | Inhibition of C-terminal His6-tagged human DNA polymerase eta (amino acids 1 to 511) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 mins | Homo sapiens | 2 | ALA1914406 | single protein format | Scientific Literature | |
7. | ALA2339794 | B | Inhibition of human DNA polymerase eta using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Homo sapiens | 1 | ALA2331167 | single protein format | Scientific Literature | |
8. | ALA3132282 | B | Inhibition of C-terminal His-6-tagged human DNA polymerase eta expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins | Homo sapiens | 4 | ALA3124747 | assay format | Scientific Literature | |
9. | ALA3215105 | F | PubChem BioAssay. qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) | 2,629 | ALA1201862 | assay format | PubChem BioAssays | ||
10. | ALA3854639 | B | Inhibition of human recombinant DNA polymerase eta expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at 2 to 6 mins by reporter-strand displacement assay | Homo sapiens | 2 | ALA3853315 | assay format | Scientific Literature | |
11. | ALA3854643 | B | Inhibition of human DNA polymerase eta (1 to 437 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition measured after 30 mins in presence of dCTP and dGTP by radioactive gel-based primer extension assay | Homo sapiens | 1 | ALA3853315 | single protein format | Scientific Literature | |
12. | ALA3854645 | B | Inhibition of C-terminal His6-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli using poly(dA)/oligo(dT)18 and [3H]dTTP as template-primer and nucleotide substrate after 60 mins | Homo sapiens | 1 | ALA3853315 | assay format | Scientific Literature |