| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA935748 | B | Inhibition of human DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG in COS cell | Homo sapiens | 19 | ALA1145628 | single protein format | Scientific Literature | |
| 2. | ALA972195 | B | Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mins | Homo sapiens | 15 | ALA1157211 | cell-based format | Scientific Literature | |
| 3. | ALA982702 | B | Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey COS7 cell membrane by scintillation counting | Homo sapiens | 22 | ALA1142489 | cell-based format | Scientific Literature | |
| 4. | ALA962982 | B | Inhibition of human recombinant DAGLalpha overexpressed in african green monkey COS7 cells | Homo sapiens | 2 | ALA1151781 | cell-based format | Scientific Literature | |
| 5. | ALA962985 | B | Inhibition of recombinant DAGLalpha overexpressed in african green monkey COS7 cells assessed as accumulation of 2-arachidonoylglycerol by Western blotting | 2 | ALA1151781 | cell-based format | Scientific Literature | ||
| 6. | ALA1227523 | B | Inhibition of recombinant DAGLalpha expressed in HEK293 cells assessed as hydrolysis of 1-stearoyl-2-arachidonoyl-glycerol to 2-AG at 25 uM after 30 mins by LC-MS method | 1 | ALA1221219 | cell-based format | Scientific Literature | ||
| 7. | ALA1227525 | B | Inhibition of recombinant DAGLalpha expressed in HEK293 cells assessed as hydrolysis of 1-stearoyl-2-arachidonoyl-glycerol to 2-AG at 10 uM after 30 mins by LC-MS method | 1 | ALA1221219 | cell-based format | Scientific Literature | ||
| 8. | ALA2176381 | B | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate in detergent free solution by FRET assay | Homo sapiens | 1 | ALA2169869 | cell-based format | Scientific Literature | |
| 9. | ALA2176382 | B | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 uM in detergent free solution by FRET assay | Homo sapiens | 13 | ALA2169869 | cell-based format | Scientific Literature | |
| 10. | ALA2176394 | B | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 uM in detergent free solution using JZL184 pretreated protein by scintillation counting based radio-TLC assay | Homo sapiens | 1 | ALA2169869 | cell-based format | Scientific Literature | |
| 11. | ALA2176395 | B | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 uM in presence of 0.015% Triton X-100 by scintillation counting based radio-TLC assay | Homo sapiens | 4 | ALA2169869 | cell-based format | Scientific Literature | |
| 12. | ALA2176396 | B | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 uM in presence of 0.05% Triton X-100 by scintillation counting based radio-TLC assay | Homo sapiens | 7 | ALA2169869 | cell-based format | Scientific Literature | |
| 13. | ALA2176397 | B | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 uM in detergent free solution by scintillation counting based radio-TLC assay | Homo sapiens | 10 | ALA2169869 | cell-based format | Scientific Literature | |
| 14. | ALA2176398 | B | Inhibition of human DAGLalpha | Homo sapiens | 2 | ALA2169869 | single protein format | Scientific Literature | |
| 15. | ALA2176399 | B | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 uM using JZL184 pretreated protein in detergent free solution by FRET assay | Homo sapiens | 10 | ALA2169869 | cell-based format | Scientific Literature | |
| 16. | ALA2176400 | B | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 uM in presence of 0.05% Triton X-100 by FRET assay | Homo sapiens | 7 | ALA2169869 | cell-based format | Scientific Literature | |
| 17. | ALA2379065 | B | Activation of human recombinant DAGLalpha expressed in African green monkey COS7 cells assessed as increase in 2-arachidonoylglycerol level per mg of extracted lipid at 1 uM preincubated for 10 mins measured after 20 mins by LC-MS analysis in presence of ionomycin (Rvb = 2.82 +/- 0.75 pmol) | Homo sapiens | 1 | ALA2375292 | cell-based format | Scientific Literature | |
| 18. | ALA2379066 | B | Activation of human recombinant DAGLalpha expressed in African green monkey COS7 cells assessed as increase in N-oleoylethanolamine level per mg of extracted lipid at 1 uM preincubated for 10 mins measured after 20 mins by LC-MS analysis in presence of ionomycin (Rvb = 1.08 +/- 0.17 pmol) | Homo sapiens | 1 | ALA2375292 | cell-based format | Scientific Literature | |
| 19. | ALA2379067 | B | Activation of human recombinant DAGLalpha expressed in African green monkey COS7 cells assessed as increase in anandamide level per mg of extracted lipid at 1 uM preincubated for 10 mins measured after 20 mins by LC-MS analysis in presence of ionomycin (Rvb = 0.16 +/- 004 pmol) | Homo sapiens | 1 | ALA2375292 | cell-based format | Scientific Literature | |
| 20. | ALA2379068 | B | Activation of human recombinant DAGLalpha expressed in African green monkey COS7 cells assessed as increase in 2-arachidonoylglycerol level per mg of extracted lipid at 3 uM preincubated for 10 mins measured after 20 mins by LC-MS analysis (Rvb = 2.82 +/- 0.75 pmol) | Homo sapiens | 1 | ALA2375292 | cell-based format | Scientific Literature |
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