| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA972423 | B | Inhibition of lipid-modified (octylated) form of SHH expressed in mouse s12 cells by luciferase reporter gene assay | 4 | ALA1138588 | cell-based format | Scientific Literature | ||
| 2. | ALA972434 | B | Binding affinity to SHH | 1 | ALA1138588 | single protein format | Scientific Literature | ||
| 3. | ALA1044701 | B | Inhibition of SHH in human HEPM cells by Gli-luciferase reporter gene assay | Homo sapiens | 1 | ALA1156025 | cell-based format | Scientific Literature | |
| 4. | ALA1101550 | B | Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonance | 18 | ALA1154349 | single protein format | Scientific Literature | ||
| 5. | ALA1220906 | B | Binding affinity to N-terminal Shh by surface plasmon resonance assay | 2 | ALA1212710 | single protein format | Scientific Literature | ||
| 6. | ALA1220917 | B | Inhibition of of N-terminal N-palmitoylated Shh-mediated Gli2 transcription in human keratinocytes at 100 uM after 30 hrs by real-time quantitative PCR analysis | Homo sapiens | 1 | ALA1212710 | cell-based format | Scientific Literature | |
| 7. | ALA1220918 | B | Inhibition of of N-terminal N-palmitoylated Shh-mediated Gli1 transcription in human keratinocytes after 30 hrs by real-time quantitative PCR analysis | Homo sapiens | 1 | ALA1212710 | cell-based format | Scientific Literature | |
| 8. | ALA1220919 | F | Inhibition of of N-terminal N-palmitoylated Shh-mediated Gli1 transcription in human keratinocytes after 30 hrs by real-time quantitative PCR analysis in presence of 3.6 uM Smo agonist purmorphamine | Homo sapiens | 1 | ALA1212710 | cell-based format | Scientific Literature | |
| 9. | ALA1220920 | F | Inhibition of of N-terminal N-palmitoylated Shh-mediated Gli1 transcription in human keratinocytes after 30 hrs by real-time quantitative PCR analysis in presence of 100 nM Smo agonist SAG | Homo sapiens | 1 | ALA1212710 | cell-based format | Scientific Literature | |
| 10. | ALA1220921 | F | Inhibition of of N-terminal N-palmitoylated Shh-mediated Gli2 transcription in human keratinocytes after 30 hrs by real-time quantitative PCR analysis in presence of 3.6 uM Smo agonist purmorphamine | Homo sapiens | 1 | ALA1212710 | cell-based format | Scientific Literature | |
| 11. | ALA1220922 | F | Inhibition of of N-terminal N-palmitoylated Shh-mediated Gli2 transcription in human keratinocytes after 30 hrs by real-time quantitative PCR analysis in presence of 100 nM Smo agonist SAG | Homo sapiens | 1 | ALA1212710 | cell-based format | Scientific Literature | |
| 12. | ALA1220923 | B | Inhibition of Shh-mediated Gli1 mRNA transcription in human synthetic skin by real-time quantitative PCR analysis | Homo sapiens | 1 | ALA1212710 | single protein format | Scientific Literature | |
| 13. | ALA1220924 | B | Inhibition of Shh-mediated Gli2 mRNA transcription in human synthetic skin by real-time quantitative PCR analysis | Homo sapiens | 1 | ALA1212710 | single protein format | Scientific Literature | |
| 14. | ALA1776927 | B | Inhibition of human SHH pathway in mouse S12 cells assessed as GLI-mediated transcriptional activity after 48 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA1772967 | cell-based format | Scientific Literature | |
| 15. | ALA1776928 | B | Inhibition of human SHH pathway in mouse S12 cells assessed as GLI-mediated transcriptional activity after 48 hrs by luciferase reporter gene assay in presence of 0.5 mg/mL human alpha-1-acid glycoprotein | Homo sapiens | 1 | ALA1772967 | cell-based format | Scientific Literature | |
| 16. | ALA1776929 | B | Inhibition of human SHH pathway in mouse S12 cells assessed as GLI-mediated transcriptional activity after 48 hrs by luciferase reporter gene assay in presence of 1 mg/mL human alpha-1-acid glycoprotein | Homo sapiens | 1 | ALA1772967 | cell-based format | Scientific Literature | |
| 17. | ALA1777114 | B | Inhibition of human SHH pathway in mouse S12 cells assessed as GLI-mediated transcriptional activity at 3 uM after 48 hrs by luciferase reporter gene assay in presence of 5 mg/mL human alpha-1-acid glycoprotein | Homo sapiens | 1 | ALA1772967 | cell-based format | Scientific Literature | |
| 18. | ALA2155375 | B | Inhibition of human Shh-induced mouse C3H10T1/2 cell differentiation after 48 hrs by alkaline phosphatase reporter assay | Homo sapiens | 2 | ALA2150854 | single protein format | Scientific Literature | |
| 19. | ALA2155376 | B | Inhibition of human Shh-induced mouse C3H10T1/2 cell differentiation after 48 hrs by alkaline phosphatase reporter assay relative to cyclopamine | Homo sapiens | 1 | ALA2150854 | single protein format | Scientific Literature | |
| 20. | ALA2162668 | B | Activation of Shh pathway in human foreskin fibroblasts assessed as increase in VEGF expression after 48 hrs by ELISA | Homo sapiens | 4 | ALA2157999 | assay format | Scientific Literature |
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