# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA678783 | B | compound was tested for the ability to function as transport substrates for the human folate-binding protein(mFBP) | 10 | ALA1130106 | single protein format | Scientific Literature | ||
2. | ALA678784 | B | compound was tested for the ability to function as transport substrates for the human folate-binding protein(mFBP); ND=not determined | 5 | ALA1130106 | single protein format | Scientific Literature | ||
3. | ALA908178 | B | Displacement of [3H]folic acid from human folate receptor expressed in KB cells relative to folic acid | Homo sapiens | 1 | ALA1137292 | cell-based format | Scientific Literature | |
4. | ALA1003024 | B | Displacement of [3H]folic acid from human folate receptor alpha in chinese hamster RT16 cells assessed as relative binding affinity relative to folic acid | Homo sapiens | 8 | ALA1138482 | cell-based format | Scientific Literature | |
5. | ALA1006405 | B | Displacement of [3H]folic acid from human FRalpha in Chinese hamster RT16 cells | Homo sapiens | 4 | ALA1156629 | cell-based format | Scientific Literature | |
6. | ALA1067644 | B | Displacement of [3H]folic acid from human FRalpha expressed in Chinese hamster RT16 cells relative to unlabeled folic acid | Homo sapiens | 6 | ALA1156866 | cell-based format | Scientific Literature | |
7. | ALA1839675 | B | Displacement of [3H]-folic acid from human FRaplha expressed in chinese hamster RT16 cells after 15 mins | Homo sapiens | 1 | ALA1833876 | cell-based format | Scientific Literature | |
8. | ALA2161355 | B | Inhibition of [3H]folic acid binding to human FRalpha expressed in CHO cells relative to folic acid | Homo sapiens | 7 | ALA2157949 | cell-based format | Scientific Literature | |
9. | ALA3088998 | B | Displacement of [3H]-folic acid from human folate receptor-alpha expressed in Chinese hamster RT16 cells after 15 mins | Homo sapiens | 6 | ALA3085726 | cell-based format | Scientific Literature | |
10. | ALA3106432 | B | Displacement of [3H]folic acid from human FRalpha expressed in chinese hamster RT16 cells after 15 mins by scintillation counting analysis | Homo sapiens | 4 | ALA3102834 | cell-based format | Scientific Literature | |
11. | ALA3387471 | B | Inhibition of FRalpha (unknown origin) expressed in Chinese hamster RT16 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-blue cell viability assay | Homo sapiens | 9 | ALA3351552 | cell-based format | Scientific Literature | |
12. | ALA3387472 | B | Inhibition of FRalpha (unknown origin) expressed in Chinese hamster RT16 cells assessed as cell growth inhibition incubated up to 96 hrs in presence of 200 nM folic acid by Celltiter-blue cell viability assay | Homo sapiens | 9 | ALA3351552 | cell-based format | Scientific Literature | |
13. | ALA3381407 | B | Inhibition of [3H]folic acid binding to FRalpha (unknown origin) expressed in Chinese hamster RT16 cells | Homo sapiens | 8 | ALA3351552 | cell-based format | Scientific Literature | |
14. | ALA3412691 | B | Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 8 | ALA3407468 | cell-based format | Scientific Literature | |
15. | ALA3632252 | B | Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
16. | ALA3632253 | B | Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay in presence of 200 nM folic acid | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
17. | ALA3632258 | B | Ratio of IC50 for human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition in presence of folic acid to IC50 for human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition in absence of folic acid | Homo sapiens | 2 | ALA3627626 | cell-based format | Scientific Literature | |
18. | ALA3632271 | B | Displacement of [3H]-folic acid from human FRalpha expressed in Chinese hamster RT16 cells after 15 mins relative to folic acid | Homo sapiens | 3 | ALA3627626 | cell-based format | Scientific Literature | |
19. | ALA3632273 | B | Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as intracellular drug level at 50 nM at 37 degC after 1 hr | Homo sapiens | 1 | ALA3627626 | cell-based format | Scientific Literature | |
20. | ALA4194629 | B | Binding affinity to human FR-alpha receptor expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell viability after 96 hrs by Cell-Titer Blue assay | Homo sapiens | 11 | ALA4190373 | cell-based format | Scientific Literature |