# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA924819 | B | Binding affinity to TrkC | 1 | ALA1147069 | single protein format | Scientific Literature | ||
2. | ALA930432 | B | Induction of TrkC tyrosine phosphorylation in transfected HEK293 cells | 1 | ALA1147069 | cell-based format | Scientific Literature | ||
3. | ALA937562 | B | Binding affinity to recombinant GST-TrkC | 1 | ALA1147069 | single protein format | Scientific Literature | ||
4. | ALA963592 | B | Binding affinity to TRKC at 10 uM by Ambit binding assay relative to control | 1 | ALA1140952 | single protein format | Scientific Literature | ||
5. | ALA974013 | B | Inhibition of TrkC by cellular assay | 2 | ALA1149823 | single protein format | Scientific Literature | ||
6. | ALA981779 | B | Inhibition of TRKC at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
7. | ALA1035905 | B | Binding affinity to human TRKC at 10 uM relative to control | Homo sapiens | 17 | ALA1151712 | single protein format | Scientific Literature | |
8. | ALA1041998 | B | Binding constant for TRKC kinase domain | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
9. | ALA1060321 | B | Inhibition of TRKC by HTRF assay | 2 | ALA1154637 | single protein format | Scientific Literature | ||
10. | ALA1059387 | B | Inhibition of TRKC assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
11. | ALA1043831 | B | Residual activity of TRK-C at 1 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
12. | ALA1072538 | B | Residual activity of TRK-C at 0.1 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
13. | ALA1073360 | B | Residual activity of TRK-C at 10 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
14. | ALA1100981 | B | Inhibition of TRKC at 10 uM | 2 | ALA1154277 | single protein format | Scientific Literature | ||
15. | ALA1111280 | B | Inhibition of TRKC at 5 uM | 1 | ALA1154316 | single protein format | Scientific Literature | ||
16. | ALA1168138 | B | Inhibition of TRKC at 1 uM | 10 | ALA1165965 | single protein format | Scientific Literature | ||
17. | ALA1175106 | B | Inhibition of TRKC at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
18. | ALA1176960 | F | Antagonist activity at human TrkC expressed in mouse NIH/3T3 cells assessed as inhibition of NT3-induced cytoprotection at 20 uM by MTT assay relative to NT3 | Homo sapiens | 1 | ALA1177730 | cell-based format | Scientific Literature | |
19. | ALA1177365 | F | Antagonist activity at human TrkC expressed in mouse NIH/3T3 cells assessed as decrease in NT3-induced TrkC-pTyr level at 20 uM after 20 mins by Western blotting | Homo sapiens | 1 | ALA1177730 | cell-based format | Scientific Literature | |
20. | ALA1177368 | B | Binding affinity at human TrkC expressed in mouse NIH/3T3 cells by FACS analysis | Homo sapiens | 1 | ALA1177730 | cell-based format | Scientific Literature |