# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA987214 | B | Inhibition of NEK5 at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
2. | ALA1062847 | B | Binding constant for NEK5 kinase domain | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
3. | ALA1048295 | B | Inhibition of NEK5 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
4. | ALA1166592 | B | Inhibition of NEK5 at 1 uM | 6 | ALA1165965 | single protein format | Scientific Literature | ||
5. | ALA1174944 | B | Inhibition of NEK5 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
6. | ALA1244538 | B | Binding affinity to NEK5 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
7. | ALA1826624 | B | Activity of NEK5 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
8. | ALA1908439 | B | Binding constant for NEK5 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
9. | ALA2215430 | B | Inhibition of NEK5 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
10. | ALA2429146 | B | Competitive binding affinity to NEK5 (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 4 | ALA2424622 | single protein format | Scientific Literature | |
11. | ALA2429175 | B | Binding affinity to NEK5 (unknown origin) | Homo sapiens | 1 | ALA2424622 | single protein format | Scientific Literature | |
12. | ALA3630740 | B | Inhibition of NEK5 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | single protein format | Scientific Literature | |
13. | ALA3748023 | B | Inhibition of human NEK5 using MBP as substrate | Homo sapiens | 1 | ALA3745707 | single protein format | Scientific Literature | |
14. | ALA4025274 | B | Inhibition of wild-type human partial length NEK5 (M1 to M279 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
15. | ALA4044085 | B | Inhibition of wild-type human partial length NEK5 (M1 to M279 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | assay format | Scientific Literature | |
16. | ALA4055226 | B | Inhibition of wild-type human partial length NEK5 (M1 to M279 residues) expressed in bacterial expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4052645 | assay format | Scientific Literature | |
17. | ALA4157164 | B | Binding affinity to wild-type human partial length NEK5 (M1 to M279 residues) expressed in bacterial expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
18. | ALA4185943 | B | Binding affinity to wild-type human partial length NEK5 (M1 to M279 residues) expressed in Escherichia coli BL21 at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | assay format | Scientific Literature | |
19. | ALA4230843 | B | Binding affinity to wild-type human partial length NEK5 (M1 to M279 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4229344 | assay format | Scientific Literature | |
20. | ALA4264432 | B | Binding affinity to wild-type human partial length NEK5 (M1 to M279 residues) expressed in bacterial expression system assessed as remaining unbound target protein level at 1000 nM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4261600 | assay format | Scientific Literature |