# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA979121 | B | Inhibition of human NTPDase 2 expressed in HEK293 cells at 1mM | Homo sapiens | 4 | ALA1155882 | cell-based format | Scientific Literature | |
2. | ALA979122 | B | Inhibition of human NTPDase 2 expressed in HEK293 cells | Homo sapiens | 9 | ALA1155882 | cell-based format | Scientific Literature | |
3. | ALA968896 | B | Inhibition of human NTPDase 2 expressed in HEK293 cells assessed as residual activity by capillary electrophoresis | Homo sapiens | 3 | ALA1155882 | cell-based format | Scientific Literature | |
4. | ALA1001639 | B | Activity of human NTPDase 2 expressed in human 293T cells assessed as drug hydrolysis at 100 uM after 20 mins relative to ATP | Homo sapiens | 3 | ALA1137702 | cell-based format | Scientific Literature | |
5. | ALA1005034 | B | Inhibition of human NTPDase 2 expressed in human 293T cells | Homo sapiens | 3 | ALA1137702 | cell-based format | Scientific Literature | |
6. | ALA1065677 | B | Inhibition of human NTPdase2 by capillary electrophoresis method | Homo sapiens | 3 | ALA1157570 | single protein format | Scientific Literature | |
7. | ALA1805823 | B | Activity of human NTPDase2 expressed in COS7 cells assessed as amount of inorganic phosphate released using ATP as the substrate at 100 uM after 15 mins by malachite green reagent method | Homo sapiens | 4 | ALA1799960 | cell-based format | Scientific Literature | |
8. | ALA1805830 | B | Inhibition of human NTPDase2 expressed in COS7 cells assessed as amount of inorganic phosphate released using ATP as the substrate at 100 uM after 15 mins by malachite green reagent method | Homo sapiens | 4 | ALA1799960 | cell-based format | Scientific Literature | |
9. | ALA2390589 | A | Drug metabolism assessed as human nucleotide triphosphate diphosphohydrolase2-mediated compound hydrolysis at 4.24 mM after 1 hr by HPLC analysis relative to ADP | Homo sapiens | 4 | ALA2384903 | single protein format | Scientific Literature | |
10. | ALA3089670 | B | Inhibition of human NTPDase2 assessed as amount of inorganic phosphate released using ATP as the substrate preincubated at 100 uM for 3 mins before substrate addition after 15 mins by malachite green reagent method | Homo sapiens | 7 | ALA3085721 | single protein format | Scientific Literature | |
11. | ALA3293335 | A | Drug metabolism assessed as human NTPDase-2-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis relative to ATP | Homo sapiens | 6 | ALA3286381 | cell-based format | Scientific Literature | |
12. | ALA3293341 | A | Drug metabolism assessed as human NTPDase-2-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis | Homo sapiens | 1 | ALA3286381 | cell-based format | Scientific Literature | |
13. | ALA3293567 | B | Inhibition of human NTPDase-2 using ATP as substrate assessed as inorganic phosphate release at 100 uM after 15 mins relative to control | Homo sapiens | 5 | ALA3286381 | single protein format | Scientific Literature | |
14. | ALA3364110 | A | Stability assessed as human NTPDase2-mediated compound hydrolysis | Homo sapiens | 9 | ALA3352222 | single protein format | Scientific Literature | |
15. | ALA3364113 | B | Inhibition of recombinant human NTPDase2 transfected in COS-7 cells using ATP substrate at 100 uM relative to control | Homo sapiens | 7 | ALA3352222 | cell-based format | Scientific Literature | |
16. | ALA3364116 | B | Inhibition of recombinant human NTPDase2 transfected in COS-7 cells using ATP substrate | Homo sapiens | 1 | ALA3352222 | cell-based format | Scientific Literature | |
17. | ALA3815627 | B | Inhibition of human recombinant NTPDase2 expressed in CHO cells using ATP as substrate at 10 to 1000 uM preincubated with substrate followed by protein addition and subsequent incubation for 30 mins by capillary electrophoresis | Homo sapiens | 1 | ALA3813632 | cell-based format | Scientific Literature | |
18. | ALA3829421 | B | Inhibition of recombinant human NTPDase2 expressed in CHO cells using ADP as substrate incubated for 10 mins by capillary electrophoresis method | Homo sapiens | 1 | ALA3826900 | cell-based format | Scientific Literature | |
19. | ALA4131385 | B | Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by malachite green reagent-based assay | Homo sapiens | 14 | ALA4130358 | assay format | Scientific Literature | |
20. | ALA4183883 | B | Inhibition of human NTPDase2 at 100 uM using ATP as substrate preincubated for 3 mins followed by substrate addition measured after 10 mins by malachite green reagent-based assay | Homo sapiens | 3 | ALA4177769 | single protein format | Scientific Literature |