| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA987166 | B | Inhibition of IRAK3 at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
| 2. | ALA1062842 | B | Binding constant for IRAK3 kinase domain | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
| 3. | ALA1053755 | B | Inhibition of IRAK3 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
| 4. | ALA1166029 | B | Inhibition of IRAK3 at 1 uM | 10 | ALA1165965 | single protein format | Scientific Literature | ||
| 5. | ALA1174669 | B | Inhibition of IRAK3 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
| 6. | ALA1244463 | B | Binding affinity to IRAK3 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
| 7. | ALA1649043 | B | Inhibition of IRAK3 at 1 uM | 1 | ALA1641548 | single protein format | Scientific Literature | ||
| 8. | ALA1826193 | B | Activity of IRAK3 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
| 9. | ALA1908763 | B | Binding constant for IRAK3 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
| 10. | ALA1944029 | B | Inhibition of IRAK3 at 1 uM | 1 | ALA1938300 | single protein format | Scientific Literature | ||
| 11. | ALA1943606 | B | Inhibition of human IRAK3 in HL-60 cells lysate assessed as reduction of labeling of acyl-phosphate ATP probe at 100 nM | Homo sapiens | 4 | ALA1938230 | cell-based format | Scientific Literature | |
| 12. | ALA2154984 | B | Binding affinity to IRAK3 | 1 | ALA2150858 | single protein format | Scientific Literature | ||
| 13. | ALA2211511 | B | Inhibition of IRAK3 | 1 | ALA2203257 | single protein format | Scientific Literature | ||
| 14. | ALA2211071 | B | Inhibition of IRAK3 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
| 15. | ALA2396461 | B | Competitive binding affinity to IRAK3 (unknown origin) assessed as enzyme remaining bound to anchored active-site ligand at 10 uM relative to control | Homo sapiens | 1 | ALA2390846 | single protein format | Scientific Literature | |
| 16. | ALA2426980 | B | Competitive binding affinity to IRAK3 (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 3 | ALA2424622 | single protein format | Scientific Literature | |
| 17. | ALA3111964 | B | Inhibition of IRAK3 (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | ALA3108735 | single protein format | Scientific Literature | |
| 18. | ALA3267555 | B | Inhibition of IRAK3 (unknown origin) at 1 uM | Homo sapiens | 1 | ALA3259517 | single protein format | Scientific Literature | |
| 19. | ALA3373403 | B | Inhibition of IRAK3 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 1 | ALA3352555 | single protein format | Scientific Literature | |
| 20. | ALA3991741 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 243 | ALA3991601 | subcellular format | Kuster lab chemical proteomics drug profiling |
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