| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA995070 | B | Inhibition of WEE2 at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
| 2. | ALA1059399 | B | Inhibition of WEE2 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
| 3. | ALA1168308 | B | Inhibition of WEE2 at 1 uM | 6 | ALA1165965 | single protein format | Scientific Literature | ||
| 4. | ALA1175120 | B | Inhibition of WEE2 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
| 5. | ALA1245024 | B | Binding affinity to WEE2 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
| 6. | ALA1827004 | B | Activity of WEE2 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
| 7. | ALA1908443 | B | Binding constant for WEE2 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
| 8. | ALA2209235 | B | Inhibition of WEE2 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
| 9. | ALA3876698 | B | Inhibition of human WEE2 (M204 to K492 residues) expressed in bacterial expression system at 1 uM by KINOMEScan assay | Homo sapiens | 1 | ALA3875204 | assay format | Scientific Literature | |
| 10. | ALA4018852 | B | Binding affinity to recombinant human full-length N-terminal His8-tagged Wee2 (1 to 567 residues) expressed in human Expi293F cells assessed as dessociation constant by quantitative real-time PCR method | Homo sapiens | 1 | ALA4017494 | cell-based format | Scientific Literature | |
| 11. | ALA4018868 | B | Binding affinity to recombinant human N-terminal His6-tagged Wee2 kinase domain (202 to 492 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry | Homo sapiens | 9 | ALA4017494 | assay format | Scientific Literature | |
| 12. | ALA4018876 | B | Binding affinity to recombinant human N-terminal His6-tagged Wee2 kinase domain (202 to 492 residues) expressed in Escherichia coli BL21 (DE3) assessed as change in melting temperature at 50 uM by differential scanning fluorimetry | Homo sapiens | 9 | ALA4017494 | assay format | Scientific Literature | |
| 13. | ALA4025437 | B | Inhibition of wild-type human partial length WEE2 (M204 to K492 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
| 14. | ALA4044248 | B | Inhibition of wild-type human partial length WEE2 (M204 to K492 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | assay format | Scientific Literature | |
| 15. | ALA4054996 | B | Inhibition of wild-type human partial length WEE1B (M204 to K492 residues) expressed in bacterial expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4052645 | assay format | Scientific Literature | |
| 16. | ALA4157327 | B | Binding affinity to wild-type human partial length WEE2 (M204 to K492 residues) expressed in bacterial expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
| 17. | ALA4186106 | B | Binding affinity to wild-type human partial length WEE2 (M204 to K492 residues) expressed in Escherichia coli BL21 at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | assay format | Scientific Literature | |
| 18. | ALA4191233 | B | Inhibition of recombinant full-length human Wee1B at 1 uM using LSNLYHQGKFLQTFCGSPLYRRR as substrate after 120 mins in presence of [gamma-33P]ATP by scintillation counting method | Homo sapiens | 1 | ALA4190187 | single protein format | Scientific Literature | |
| 19. | ALA4231006 | B | Binding affinity to wild-type human partial length WEE2 (M204 to K492 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4229344 | assay format | Scientific Literature | |
| 20. | ALA4264595 | B | Binding affinity to wild-type human partial length WEE2 (M204 to K492 residues) expressed in bacterial expression system assessed as remaining unbound target protein level at 1000 nM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4261600 | assay format | Scientific Literature |
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