# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1032396 | B | Inhibition of FtsZ-mediated cell division in Staphylococcus aureus ATCC 29213 assessed as drug concentration required to produce ballooning | Staphylococcus aureus | 5 | ALA1154532 | single protein format | Scientific Literature | |
2. | ALA1014176 | B | Inhibition of Staphylococcus aureus FtsZ GTPase activity | Staphylococcus aureus | 1 | ALA1152869 | single protein format | Scientific Literature | |
3. | ALA1113793 | B | Inhibition of Staphylococcus aureus ATCC 29213 FtsZ assessed as lowest drug level required for ballooning of cells by light microscopy | Staphylococcus aureus | 24 | ALA1157799 | assay format | Scientific Literature | |
4. | ALA1113794 | B | Inhibition of Staphylococcus aureus ATCC 29213 FtsZ assessed as appearance of enlarged cells at 2048 to 4096 ug/mL by light microscopy | Staphylococcus aureus | 14 | ALA1157799 | assay format | Scientific Literature | |
5. | ALA2162977 | B | Induction of Staphylococcus aureus FtsZ self-polymerization assessed as increase in light scattering at 10 ug/mL by 90 deg angle light scattering assay | Staphylococcus aureus | 1 | ALA2157956 | single protein format | Scientific Literature | |
6. | ALA2162978 | B | Induction of Staphylococcus aureus FtsZ self-polymerization assessed as increase in light scattering at 20 ug/mL by 90 deg angle light scattering assay | Staphylococcus aureus | 2 | ALA2157956 | single protein format | Scientific Literature | |
7. | ALA2162979 | B | Induction of Staphylococcus aureus FtsZ self-polymerization assessed as increase in light scattering at 20 ug/mL measured every 5 secs by 90 deg angle light scattering assay | Staphylococcus aureus | 1 | ALA2157956 | single protein format | Scientific Literature | |
8. | ALA2162980 | B | Inhibition of Staphylococcus aureus FtsZ self-polymerization assessed as decrease in light scattering at 20 ug/mL by 90 deg angle light scattering assay | Staphylococcus aureus | 1 | ALA2157956 | single protein format | Scientific Literature | |
9. | ALA2183442 | B | Binding affinity to Staphylococcus aureus FtsZ G196A mutant self-polymerization at 20 ug/mL by microtiter plate-based light scattering assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
10. | ALA2183443 | B | Binding affinity to Staphylococcus aureus FtsZ G196A mutant self-polymerization at 10 ug/mL by microtiter plate-based light scattering assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
11. | ALA2183444 | B | Binding affinity to Staphylococcus aureus FtsZ I228R mutant self-polymerization at 20 ug/mL by microtiter plate-based light scattering assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
12. | ALA2183445 | B | Binding affinity to Staphylococcus aureus FtsZ I228R mutant self-polymerization at 10 ug/mL by microtiter plate-based light scattering assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
13. | ALA2183446 | B | Binding affinity to Staphylococcus aureus FtsZ E185A mutant self-polymerization at 20 ug/mL by microtiter plate-based light scattering assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
14. | ALA2183447 | B | Binding affinity to Staphylococcus aureus FtsZ E185A mutant self-polymerization at 10 ug/mL by microtiter plate-based light scattering assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
15. | ALA2183448 | B | Binding affinity to Staphylococcus aureus FtsZ G196A mutant expressed in Escherichia coli BL21 (DE3) at 25 degC by fluorescence anisotropy assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
16. | ALA2183449 | B | Binding affinity to Staphylococcus aureus FtsZ I228R mutant expressed in Escherichia coli BL21 (DE3) at 25 degC by fluorescence anisotropy assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
17. | ALA2183450 | B | Binding affinity to Staphylococcus aureus FtsZ E185A mutant expressed in Escherichia coli BL21 (DE3) at 25 degC by fluorescence anisotropy assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
18. | ALA2183453 | B | Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli BL21 (DE3) at 40 uM by fluorescence anisotropy BoGTPgammaS competition assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
19. | ALA2183456 | B | Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli BL21 (DE3) by fluorescence anisotropy BoGTPgammaS competition assay | Staphylococcus aureus | 1 | ALA2176974 | assay format | Scientific Literature | |
20. | ALA2183458 | B | Stimulation of Staphylococcus aureus FtsZ assembly and bundling at 20 ug/mL by transmission electron microscopy | Staphylococcus aureus | 1 | ALA2176974 | single protein format | Scientific Literature |