# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA926786 | B | Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assay | Mus musculus | 27 | ALA1140726 | cell-based format | Scientific Literature | |
2. | ALA953995 | B | Inhibition of mouse recombinant Nav1.8 channel expressed in HEK293 cells by isotopic efflux assay | Mus musculus | 10 | ALA1150418 | cell-based format | Scientific Literature | |
3. | ALA1272887 | B | Inhibition of mouse NaV1.8 by electrophysiology | Mus musculus | 25 | ALA1268885 | single protein format | Scientific Literature | |
4. | ALA1286451 | B | Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assay | Mus musculus | 23 | ALA1275385 | cell-based format | Scientific Literature | |
5. | ALA3992721 | B | Inhibition of Nav1.8 in mouse DRG neurons assessed as inhibition of TTX-resistant current at 10 uM at holding potential of -120 mV by manual patch electrophysiology method | Mus musculus | 2 | ALA3992487 | single protein format | Scientific Literature | |
6. | ALA4055950 | B | Inhibition of NaV1.8 in C57BL/6 mouse DRG neurons assessed as reduction in tetrodotoxin-sensitive sodium channel currents at holding potential of -140 mV by manual patch clamp electrophysiology assay | Mus musculus | 1 | ALA4052683 | assay format | Scientific Literature | |
7. | ALA4322025 | B | Binding affinity to mouse Nav1.8 TTX-resistant current by radioligand binding assay | Mus musculus | 2 | ALA4321785 | single protein format | Scientific Literature | |
8. | ALA4386314 | B | Inhibition of Nav1.8 in C57BL/6 mouse DRG neurons assessed as reduction in TTX resistant sodium channel-mediated currents up to >3000 nM at -60 mV holding potential by manual patch clamp electrophysiology method | Mus musculus | 1 | ALA4385607 | assay format | Scientific Literature | |
9. | ALA5264218 | B | Inhibition of TTX-resistant Nav1.8 in mouse dorsal root ganglion neuron at 10 uM by voltage clamp recording relative to control | Mus musculus | 2 | ALA5260838 | tissue-based format | Scientific Literature | |
10. | ALA5264219 | B | Inhibition of TTX-resistant Nav1.8 in mouse dorsal root ganglion neuron by voltage clamp recording | Mus musculus | 2 | ALA5260838 | tissue-based format | Scientific Literature |