# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA962232 | B | Inhibition of DAGLalpha in mouse brain assessed as >15 average spectral count at 50 uM treated for 30 mins by ABPP-MudPIT assay | Mus musculus | 2 | ALA1151781 | tissue-based format | Scientific Literature | |
2. | ALA962974 | B | Inhibition of DAGLalpha in mouse brain assessed as >15 average spectral count at 5 uM treated for 30 mins by ABPP-MudPIT assay | Mus musculus | 2 | ALA1151781 | tissue-based format | Scientific Literature | |
3. | ALA2176383 | B | Inhibition of mouse DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10000 nM by scintillation counting based radio-TLC assay | Mus musculus | 11 | ALA2169869 | cell-based format | Scientific Literature | |
4. | ALA2176384 | B | Inhibition of mouse DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 1000 nM by scintillation counting based radio-TLC assay | Mus musculus | 11 | ALA2169869 | cell-based format | Scientific Literature | |
5. | ALA2176385 | B | Inhibition of mouse DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 100 nM by scintillation counting based radio-TLC assay | Mus musculus | 11 | ALA2169869 | cell-based format | Scientific Literature | |
6. | ALA2176386 | B | Inhibition of mouse DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 nM by scintillation counting based radio-TLC assay | Mus musculus | 15 | ALA2169869 | cell-based format | Scientific Literature | |
7. | ALA3373888 | B | Inhibition of MB064 labeling of DAGLalpha in mouse brain homogenates by activity based protein profiling assay | Mus musculus | 4 | ALA3352769 | tissue-based format | Scientific Literature | |
8. | ALA3373890 | B | Inhibition of TAMRA-FP labeling of DAGLalpha in mouse brain homogenates by activity based protein profiling assay | Mus musculus | 4 | ALA3352769 | tissue-based format | Scientific Literature | |
9. | ALA3768668 | B | Inhibition of DAGLalpha in mouse N18TG2 cells assessed as inhibition of ionomycin-induced formation of 2-AG incubated for 20 mins by LC-MS analysis | Mus musculus | 1 | ALA3763072 | cell-based format | Scientific Literature | |
10. | ALA3879169 | B | Inhibition of MB064 probe binding to DAGLalpha in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured after 20 mins by gel-based competitive activity based protein profiling assay | Mus musculus | 7 | ALA3877306 | cell membrane format | Scientific Literature | |
11. | ALA4262258 | B | Inhibition of MB064 labelling of DAGLalpha in mouse brain homogenates at 10 uM pretreated for 30 mins followed by MB064 addition and measured after 20 mins by activity based protein profiling assay relative to control | Mus musculus | 22 | ALA4261499 | tissue-based format | Scientific Literature | |
12. | ALA4376250 | B | Inhibition of mouse DAGL-alpha expressed in HEK293T cell membranes pre-incubated for 20 mins before PNP-butyrate substrate addition and measured after 30 mins by surrogate substrate assay | Mus musculus | 8 | ALA4373725 | cell-based format | Scientific Literature | |
13. | ALA4376251 | B | Inhibition of mouse DAGL-alpha expressed in HEK293T cell membranes assessed as inhibition constant pre-incubated for 20 mins before PNP-butyrate substrate addition and measured after 30 mins by surrogate substrate assay | Mus musculus | 8 | ALA4373725 | cell-based format | Scientific Literature | |
14. | ALA4376252 | B | Inhibition of mouse DAGL-alpha expressed in HEK293T cell membranes assessed as inactivation constant pre-incubated for 20 mins before PNP-butyrate substrate addition and measured after 30 mins by surrogate substrate assay | Mus musculus | 7 | ALA4373725 | cell-based format | Scientific Literature | |
15. | ALA4427018 | B | Inhibition of DAGLalpha in mouse brain proteome pre-incubated for 30 mins followed by ABP MB064 probe addition for 15 mins by ABPP assay | Mus musculus | 3 | ALA4425142 | subcellular format | Scientific Literature | |
16. | ALA4626927 | B | Inhibition of mouse brain membrane DAGLalpha assessed as enzyme remaining activity at 10 uM preincubated for 30 mins followed by MB064 or FP-TAMRA addition and measured after 15 mins by SDS-PAGE based ABPP analysis relative to control | Mus musculus | 1 | ALA4622983 | cell membrane format | Scientific Literature |