#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA1023797	B	Binding affinity to mouse P2X7 channel	Mus musculus	1	ALA1140148	single protein format	Scientific Literature
2.	ALA1048351	B	Binding affinity at mouse P2X7 receptor	Mus musculus	1	ALA1154101	single protein format	Scientific Literature
3.	ALA1780726	F	Antagonist activity at P2X7 receptor in mouse LPS-stimulated peritoneal macrophages assessed as inhibition of ATP-induced IL1-beta release at 10 uM by ELISA	Mus musculus	1	ALA1777794	assay format	Scientific Literature
4.	ALA2344145	B	Antagonist activity at mouse P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assay	Mus musculus	2	ALA2331410	single protein format	Scientific Literature
5.	ALA3418723	B	Antagonist activity at P2X7 receptor in LPS-primed mouse J774.A1 cells assessed as inhibition of ATP-induced IL-1beta release after 30 mins by ELISA	Mus musculus	2	ALA3414458	cell-based format	Scientific Literature
6.	ALA3858377	B	Antagonist activity at recombinant mouse P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of Bz-ATP-induced Ca2+ flux preincubated for 30 mins followed by agonist addition measured after 180 sec by calcium-4 dye based FLIPR assay	Mus musculus	4	ALA3856233	cell-based format	Scientific Literature
7.	ALA3858388	B	Antagonist activity at P2X7 receptor in LPS-stimulated mouse whole blood assessed as inhibition of Bz-ATP-induced IL-1beta release incubated for 30 mins after LPS stimulation for 1 hr followed by agonist addition measured after 1.5 hrs by ELISA	Mus musculus	1	ALA3856233	tissue-based format	Scientific Literature
8.	ALA3859177	B	Antagonist activity at mouse P2X7 receptor assessed as reduction in calcium flux by FLIPR calcium flux assay	Mus musculus	9	ALA3856256	single protein format	Scientific Literature
9.	ALA3859179	B	Antagonist activity at P2X7 receptor in C57/bl6 mouse whole blood assessed as reduction in LPS/BzATP-induced IL-1beta release preincubated with LPS-stimulated cells for 30 mins followed by BzATP addition measured after 1.5 hrs by ELISA	Mus musculus	3	ALA3856256	tissue-based format	Scientific Literature
10.	ALA4012088	B	Antagonist activity at mouse P2X7 receptor expressed in 1321N1 cells assessed as inhibition of agonist-induced calcium flux pretreated for 3 mins followed by BzATP addition after 3 mins measured every 1 sec for 60 secs and at 5 secs interval throughout testing by Flou-4-AM dye based FLIPR assay	Mus musculus	1	ALA4011591	cell-based format	Scientific Literature
11.	ALA4054682	B	Antagonist activity at P2X7 in mouse whole blood assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins followed by BzATP addition measured after 1.5 hrs by ELISA	Mus musculus	1	ALA4052642	single protein format	Scientific Literature
12.	ALA4054688	B	Antagonist activity at mouse P2X7 assessed as inhibition of BzATP-induced calcium flux preincubated for 30 mins followed by BzATP addition measured over 180 secs by FLIPR assay	Mus musculus	1	ALA4052642	single protein format	Scientific Literature
13.	ALA4133142	B	Antagonist activity at mouse P2X7 receptor expressed in human 1321N1 cells assessed as reduction in agonist-induced intracellular Ca2+ levels preincubated for 3 mins followed by agonist addition measured up to 2 mins by Fluo-4 dye-based FLIPR assay	Mus musculus	1	ALA4130413	cell-based format	Scientific Literature
14.	ALA4133148	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake after 25 mins by flow cytometric analysis	Mus musculus	8	ALA4130413	single protein format	Scientific Literature
15.	ALA4133149	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced current at holding potential of -60 mV preincubated for 5 mins followed by ATP addition measured after 5 mins by Whole cell patch-clamp analysis	Mus musculus	8	ALA4130413	single protein format	Scientific Literature
16.	ALA4133152	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of BzATP-induced ethidium iodide uptake after 30 mins by spectrofluorometric analysis	Mus musculus	3	ALA4130413	single protein format	Scientific Literature
17.	ALA4133153	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of BzATP-induced current at holding potential of -60 mV preincubated for 5 mins followed by BzATP addition measured after 5 mins by Whole cell patch-clamp analysis	Mus musculus	3	ALA4130413	single protein format	Scientific Literature
18.	ALA4133155	B	Antagonist activity at P2X7 receptor in LPS/IFNc-differentiated Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced IL-1beta release preincubated for 30 mins followed by LPS stimulation for 4 hrs using cells treated with ATP for 15 mins by ELISA	Mus musculus	2	ALA4130413	assay format	Scientific Literature
19.	ALA4133197	B	Antagonist activity at mouse P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake at 10 uM preincubated for 10 mins followed by ATP addition measured after 20 mins by FLIPR assay relative to 1 mM ATP	Mus musculus	7	ALA4130413	cell-based format	Scientific Literature
20.	ALA4219900	B	Agonist activity at P2X7 receptor in C57Bl6 mouse lumbar spinal cord slices assessed as increase in glycinergic inhibitory postsynaptic currents after 20 to 26 mins by electrophysiology method relative to control	Mus musculus	1	ALA4219040	single protein format	Scientific Literature