# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1034185 | B | Blockade of voltage-activated rat Kv1.1 potassium channel expressed in Xenopus laevis oocytes assessed as effect on evoked current upto 10 uM by two-electrode voltage clamp method | Rattus norvegicus | 4 | ALA1137811 | cell-based format | Scientific Literature | |
2. | ALA4009549 | B | Inhibition of recombinant rat Kv1.1 expressed in HEK293 cells assessed as time constant for activation of Kv1.1 channel current at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method (Rvb = 1.9 +/- 0.15 ms) | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
3. | ALA4009550 | B | Inhibition of recombinant rat Kv1.1 expressed in HEK293 cells assessed as shift of half maximal vale for activation at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
4. | ALA4009551 | B | Inhibition of recombinant rat Kv1.1 expressed in HEK293 cells at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method relative to control | Rattus norvegicus | 3 | ALA4007435 | cell-based format | Scientific Literature | |
5. | ALA4009557 | B | Inhibition of recombinant rat Kv1.1 expressed in HEK293 cells at -90 mV holding potential by whole cell patch clamp Qpatch method | Rattus norvegicus | 2 | ALA4007435 | cell-based format | Scientific Literature | |
6. | ALA4009558 | B | Inhibition of recombinant rat Kv(1.1)4 expressed in HEK293 cells at -90 mV holding potential by whole cell patch clamp Qpatch method | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
7. | ALA4009566 | B | Inhibition of recombinant rat Kv1.1 concatamer expressed in HEK293 cells assessed as time constant for activation of Kv1.1 channel current at -90 mV holding potential by whole cell patch clamp Qpatch method (Rvb = 2.2 +/- 0.1 ms) | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
8. | ALA4193576 | B | Inhibition of rat Kv1.1 expressed in Xenopus laevis oocytes at 1 uM at -90 mV holding potential by two-electrode voltage clamp assay relative to control | Rattus norvegicus | 18 | ALA4190320 | cell-based format | Scientific Literature | |
9. | ALA4882215 | B | K+/KA/R Eurofins-Panlabs selectivity data (BI) | Rattus norvegicus | 1 | ALA4507277 | single protein format | Donated Chemical Probes - SGC Frankfurt | |
10. | ALA4887086 | B | K+/KA/R Eurofins-Panlabs selectivity data (BI) | Rattus norvegicus | 1 | ALA4507282 | single protein format | Donated Chemical Probes - SGC Frankfurt | |
11. | ALA5125252 | B | Effect on rat Kv1.1 expressed in Xenopus laevis oocytes at 10 uM at holding potential of -90 mV by patch clamp electrophysiology | Rattus norvegicus | 1 | ALA5120921 | cell-based format | Scientific Literature |