# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA925835 | B | Inhibition of Clostridium botulinum recombinant BoNT/A light chain toxin expressed in Escherichia coli by FRET assay | Clostridium botulinum | 7 | assay format | Scientific Literature | ||
2. | ALA925836 | B | Reduction of Clostridium botulinum recombinant BoNT/A light chain-mediated intracellular SNAP25 peptide cleavage in mouse Neuro2a cells at 25 uM after 48 hrs | Clostridium botulinum | 1 | cell-based format | Scientific Literature | ||
3. | ALA997861 | B | Inhibition of Clostridium botulinum neurotoxin serotype A light chain metalloprotease activity | Clostridium botulinum | 7 | single protein format | Scientific Literature | ||
4. | ALA961806 | B | Inhibition of Clostridium botulinum recombinant Bont/A light chain expressed in Escherichia coli BL21 GOLD | Clostridium botulinum | 14 | assay format | Scientific Literature | ||
5. | ALA961807 | B | Inhibition of Clostridium botulinum recombinant Bont/A light chain expressed in Escherichia coli BL21 GOLD at 50 uM | Clostridium botulinum | 2 | assay format | Scientific Literature | ||
6. | ALA961808 | B | Inhibition of Clostridium botulinum recombinant Bont/A light chain | Clostridium botulinum | 2 | single protein format | Scientific Literature | ||
7. | ALA1047164 | B | Inhibition of Clostridium botulinum neurotoxin A light chain by FRET-based assay | Clostridium botulinum | 1 | single protein format | Scientific Literature | ||
8. | ALA1047165 | B | Inhibition of Clostridium botulinum neurotoxin A light chain by HPLC-based assay | Clostridium botulinum | 5 | single protein format | Scientific Literature | ||
9. | ALA1047166 | B | Inhibition of Clostridium botulinum neurotoxin A light chain at 20 uM by HPLC-based assay | Clostridium botulinum | 3 | single protein format | Scientific Literature | ||
10. | ALA1069850 | B | Inhibition of Clostridium botulinum BoNT/A | Clostridium botulinum | 3 | single protein format | Scientific Literature | ||
11. | ALA1069851 | B | Ratio of Kinact to Ki for Clostridium botulinum BoNT/A | Clostridium botulinum | 3 | single protein format | Scientific Literature | ||
12. | ALA1071240 | B | Inhibition of Clostridium botulinum BoNT/A expressed in rat spinal cord neuron assessed as decrease in SNAP25 cleavage up to 600 uM | Clostridium botulinum | 2 | assay format | Scientific Literature | ||
13. | ALA1071241 | B | Inhibition of Clostridium botulinum BoNT/A expressed in rat spinal cord neuron assessed as cleavage of target protein SNAP25 at 62.5 uM | Clostridium botulinum | 1 | assay format | Scientific Literature | ||
14. | ALA1071242 | B | Inhibition of Clostridium botulinum BoNT/A expressed in rat spinal cord neuron assessed as cleavage of target protein SNAP25 at 125 uM | Clostridium botulinum | 1 | assay format | Scientific Literature | ||
15. | ALA1067450 | B | Inhibition of Clostridium botulinum toxin BoNT/A light chain by FRET assay | Clostridium botulinum | 32 | single protein format | Scientific Literature | ||
16. | ALA1067451 | B | Inhibition of Clostridium botulinum toxin BoNT/A light chain by HPLC-based assay | Clostridium botulinum | 9 | single protein format | Scientific Literature | ||
17. | ALA1067457 | B | Inhibition of Clostridium botulinum toxin BoNT/A light chain | Clostridium botulinum | 3 | single protein format | Scientific Literature | ||
18. | ALA1067458 | B | Inhibition of Clostridium botulinum toxin BoNT/A light chain at 20 uM by FRET assay | Clostridium botulinum | 1 | single protein format | Scientific Literature | ||
19. | ALA1697028 | B | Binding affinity to Clostridium botulinum BoNT/A | Clostridium botulinum | 1 | single protein format | Scientific Literature | ||
20. | ALA1697029 | B | Inhibition of Clostridium botulinum BoNT/A-mediated neuromuscular block in CD1 mouse phrenic nerve hemidiaphragm assessed as time required to 50% loss of twitch tension at 0.5 uM after 15 to 20 mins | Clostridium botulinum | 1 | single protein format | Scientific Literature |