| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2040353 | B | Inhibition of clostridium botulinum Botulinum neurotoxin type A light chain at 20 uM by RP-HPLC analysis | Clostridium botulinum | 1 | single protein format | Scientific Literature | ||
| 2. | ALA2040354 | B | Competitive inhibition of clostridium botulinum Botulinum neurotoxin type A light chain by RP-HPLC analysis | Clostridium botulinum | 7 | single protein format | Scientific Literature | ||
| 3. | ALA2040355 | B | Ratio of Ki for NSC 300510 to compound Ki for clostridium botulinum Botulinum neurotoxin type A light chain by RP-HPLC analysis | Clostridium botulinum | 2 | single protein format | Scientific Literature | ||
| 4. | ALA2038925 | B | Inhibition of Clostridium botulinum BoNT/A light chain assessed as inhibition of SNAP-25 (187-203) substrate hydrolysis by RP-HPLC-based assay in presence of excess Zn(II) | Clostridium botulinum | 4 | single protein format | Scientific Literature | ||
| 5. | ALA2038926 | B | Competitive inhibition of Clostridium botulinum BoNT/A light chain assessed as inhibition of SNAP-25 (187-203) substrate hydrolysis by Dixon plot analysis | Clostridium botulinum | 3 | single protein format | Scientific Literature | ||
| 6. | ALA2033254 | B | Inhibition of clostridium botulinum Botulinum neurotoxin type A using SNAPide as substrate by FRET analysis | Clostridium botulinum | 44 | single protein format | Scientific Literature | ||
| 7. | ALA1936262 | B | Inhibition of Clostridium botulinum botulinum neurotoxin type A light chain | Clostridium botulinum | 1 | single protein format | Scientific Literature | ||
| 8. | ALA1936263 | B | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage after 40 mins by FRET assay | Clostridium botulinum | 29 | single protein format | Scientific Literature | ||
| 9. | ALA1936264 | B | Inhibition of Clostridium botulinum BoNT/A light chain after 40 mins by HPLC assay | Clostridium botulinum | 2 | single protein format | Scientific Literature | ||
| 10. | ALA1936940 | B | Inhibition of clostridium botulinum BoNT/A-mediated SNAP-25 substrate cleavage in chicken neurons at 30 uM preincubated for 15 mins before substrate addition | Clostridium botulinum | 3 | single protein format | Scientific Literature | ||
| 11. | ALA1936941 | B | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage preincubated for 15 mins in presence of zinc ion before substrate addition by FRET assay | Clostridium botulinum | 2 | single protein format | Scientific Literature | ||
| 12. | ALA1936942 | B | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage preincubated for 15 mins in presence of glutathione before substrate addition by FRET assay | Clostridium botulinum | 2 | single protein format | Scientific Literature | ||
| 13. | ALA1936943 | B | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage preincubated for 15 mins in presence of cysteine before substrate addition by FRET assay | Clostridium botulinum | 2 | single protein format | Scientific Literature | ||
| 14. | ALA1936944 | B | Ratio of Kinact to Ki for clostridium botulinum BoNT/A light chain | Clostridium botulinum | 2 | single protein format | Scientific Literature | ||
| 15. | ALA1936945 | B | Inhibition of clostridium botulinum BoNT/A light chain assessed as residual activity using SNAP-25 as substrate at 50 uM after 90 mins measured after dialysis by FRET-based assay relative to control | Clostridium botulinum | 3 | single protein format | Scientific Literature | ||
| 16. | ALA1936946 | B | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage preincubated for 90 mins by FRET assay | Clostridium botulinum | 1 | single protein format | Scientific Literature | ||
| 17. | ALA1936947 | B | Time dependent inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage by FRET assay | Clostridium botulinum | 1 | single protein format | Scientific Literature | ||
| 18. | ALA1936948 | B | Inhibition of clostridium botulinum BoNT/A light chain assessed as residual activity using SNAP-25 as substrate at 50 uM after 90 mins measured after dialysis by FRET-based assay relative to 6-(4,5-dihydro-1H-imidazol-2-yl)-2-(4-(4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy)phenyl)-1H-indole | Clostridium botulinum | 2 | single protein format | Scientific Literature | ||
| 19. | ALA2162849 | B | Inhibition of Clostridium botulinum neurotoxin serotype A light chain at 5 uM preincubated for 5 mins before SNAPtid substrate addition by FRET assay | Clostridium botulinum | 1 | single protein format | Scientific Literature | ||
| 20. | ALA2162850 | B | Non-competitive inhibition of Clostridium botulinum neurotoxin serotype A light chain using 66-mer peptide by LC/MS assay | Clostridium botulinum | 1 | single protein format | Scientific Literature |
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