| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA995066 | B | Inhibition of TNNI3K at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
| 2. | ALA1061932 | B | Binding constant for full-length TNNI3K | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
| 3. | ALA1059384 | B | Inhibition of TNNI3K assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
| 4. | ALA1168135 | B | Inhibition of TNNI3K at 1 uM | 10 | ALA1165965 | single protein format | Scientific Literature | ||
| 5. | ALA1175103 | B | Inhibition of TNNI3K at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
| 6. | ALA1245009 | B | Binding affinity to TNNI3K | 7 | ALA1240346 | single protein format | Scientific Literature | ||
| 7. | ALA1826997 | B | Activity of TNNI3K kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
| 8. | ALA1908794 | B | Binding constant for TNNI3K kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
| 9. | ALA2209251 | B | Inhibition of TNNI3K assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
| 10. | ALA2428860 | B | Competitive binding affinity to TNN13K (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 4 | ALA2424622 | single protein format | Scientific Literature | |
| 11. | ALA3111559 | B | Inhibition of TNNI3K (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | ALA3108735 | single protein format | Scientific Literature | |
| 12. | ALA3615798 | B | Binding affinity to TNNI3K (unknown origin) | Homo sapiens | 1 | ALA3611990 | single protein format | Scientific Literature | |
| 13. | ALA3615799 | B | Displacement of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid from His6-MBP-TEV-full length human TNNI3K expressed in Baculovirus expression system after 60 mins by fluorescence polarization assay | Homo sapiens | 57 | ALA3611990 | assay format | Scientific Literature | |
| 14. | ALA3616263 | B | Inhibition of human myc-tagged TNNI3K autophosphorylation overexpressed in HEKMSRII cells preincubated for 30 mins followed by pervanadate solution addition measured after 20 mins by DELFIA | Homo sapiens | 10 | ALA3611990 | cell-based format | Scientific Literature | |
| 15. | ALA3816884 | B | Displacement of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid from full length human TNNI3K expressed in baculovirus system incubated for 60 mins by fluorescence polarization assay | Homo sapiens | 30 | ALA3813650 | assay format | Scientific Literature | |
| 16. | ALA3816952 | B | Inhibition of human myc-tagged TNNI3K autophosphorylation overexpressed in HEKMSR2 cells incubated for 30 mins by time resolved fluorescence assay | Homo sapiens | 13 | ALA3813650 | cell-based format | Scientific Literature | |
| 17. | ALA3861903 | B | Displacement of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid from His6-MBP-TEV-full length human TNNI3K expressed in Baculovirus expression system after 60 mins by fluorescence polarization assay | Homo sapiens | 62 | ALA3860108 | assay format | Scientific Literature | |
| 18. | ALA3994951 | B | Inhibition of full length human TNNI3K (M1 to S835 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by KINOMEscan assay relative to control | Homo sapiens | 1 | ALA3994581 | assay format | Scientific Literature | |
| 19. | ALA4024626 | B | Inhibition of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid binding to human full length His/MBP-fused TNNI3K expressed in baculovirus expression system after 60 mins by fluorescence polarization assay | Homo sapiens | 45 | ALA4020849 | assay format | Scientific Literature | |
| 20. | ALA4024627 | B | Inhibition of human Myc-tagged TNNI3K autophosphorylation expressed in HEKMSR2 cells after 30 mins by DELFIA | Homo sapiens | 4 | ALA4020849 | cell-based format | Scientific Literature |
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