| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA968038 | F | Agonist activity at rat GPR119 transfected in Xenopus dermal melanophore assessed as dispersion of melatonin-induced pigmentation | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 2. | ALA1769446 | F | Agonist activity at rat GPR119 expressed in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA1769547 | F | Intrinsic activity at rat GPR119 expressed in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assay relative to WO2005121121 | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA1769550 | B | Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate from rat GPR119 expressed in human HEK293 cells by liquid scintillation counting | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA1775790 | B | Selectivity ratio of EC50 for rat GPR119 to EC50 for human GPR119 | Rattus norvegicus | 29 | single protein format | Scientific Literature | ||
| 6. | ALA1775791 | F | Agonist activity at rat GPR119 by melanophore assay | Rattus norvegicus | 29 | assay format | Scientific Literature | ||
| 7. | ALA1953650 | F | Agonist activity at rat GPR119 receptor assessed as cAMP production by HTRF assay | Rattus norvegicus | 30 | assay format | Scientific Literature | ||
| 8. | ALA1953652 | F | Intrinsic activity at rat GPR119 receptor assessed as cAMP production by HTRF assay relative to AR231453 | Rattus norvegicus | 21 | single protein format | Scientific Literature | ||
| 9. | ALA3106557 | F | Agonist activity at rat GPR119 assessed as cAMP accumulation | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 10. | ALA3374950 | F | Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assay | Rattus norvegicus | 36 | single protein format | Scientific Literature | ||
| 11. | ALA3374951 | F | Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assay relative to AR231453 | Rattus norvegicus | 36 | single protein format | Scientific Literature | ||
| 12. | ALA3599707 | F | Agonist activity at rat GPR119 by HTRF cAMP assay | Rattus norvegicus | 37 | single protein format | Scientific Literature | ||
| 13. | ALA3599708 | F | Agonist activity at rat GPR119 by HTRF cAMP assay relative to AR231453 | Rattus norvegicus | 37 | single protein format | Scientific Literature | ||
| 14. | ALA4724809 | B | Agonist activity at rat GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4812962 | F | Agonist activity at rat GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by steady-glo luciferase assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4812963 | F | Agonist activity at rat GPR119 in golden hamster HIT-T15 cells assessed as induction of glucose-induced insulin secretion after 2 hrs by A1phaLISA | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 17. | ALA4812964 | F | Agonist activity at rat GPR119 in GLUTag cells assessed as induction of GLP-1 secretion after 2 hrs by ELISA | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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