| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA990279 | B | Inhibition calf thymus topoisomerase 1 cleavage activity assessed as increase in nicked pBR322 DNA formation after 40 mins by gel electrophoresis | Bos taurus | 2 | ALA1155708 | single protein format | Scientific Literature | |
| 2. | ALA996004 | B | Inhibition calf thymus gland topoisomerase 1 assessed as conversion of supercoiled pBR322 DNA to relaxed form | Bos taurus | 4 | ALA1155708 | single protein format | Scientific Literature | |
| 3. | ALA996016 | B | Activity at calf thymus gland topoisomerase 1 assessed as conversion of supercoiled pBR322 DNA to relaxed form by Lineweaver-Burke plot | Bos taurus | 1 | ALA1155708 | single protein format | Scientific Literature | |
| 4. | ALA3384080 | B | Inhibition of calf thymus DNA topoisomerase 1 assessed as reduction in pBR322 DNA relaxation at 100 uM incubated for 30 mins by DNA gel electrophoresis | Bos taurus | 5 | ALA3351570 | single protein format | Scientific Literature | |
| 5. | ALA3383706 | B | Inhibition of calf thymus Topoisomerase 1-mediated relaxation of supercoiled pBR322 DNA at 100 uM after 30 mins by gel electrophoresis | Bos taurus | 13 | ALA3352321 | single protein format | Scientific Literature | |
| 6. | ALA3413604 | B | Induction of calf thymus Topo 1-pBR322 DNA cleavage complex formation assessed as nicked DNA formation after 30 mins by agarose gel electrophoresis | Bos taurus | 1 | ALA3407378 | single protein format | Scientific Literature | |
| 7. | ALA3413605 | B | Induction of calf thymus Topo 1-pBR322 DNA cleavage complex formation assessed as nicked DNA formation at 0.5 to 10 uM after 30 mins by optical density analysis | Bos taurus | 1 | ALA3407378 | single protein format | Scientific Literature | |
| 8. | ALA3413606 | B | Induction of calf thymus Topo 1-pBR322 DNA cleavage complex formation assessed as nicked DNA formation at 10 uM after 30 mins by optical density analysis relative to control | Bos taurus | 1 | ALA3407378 | single protein format | Scientific Literature | |
| 9. | ALA3413607 | B | Induction of calf thymus Topo 1-pBR322 DNA cleavage complex formation assessed as nicked DNA formation at 25 to 50 uM after 30 mins by optical density analysis relative to control | Bos taurus | 1 | ALA3407378 | single protein format | Scientific Literature | |
| 10. | ALA3428764 | B | Inhibition of calf thymus Topoisomerase 1 relaxation activity by plasmid relaxation assay | Bos taurus | 12 | ALA3425421 | single protein format | Scientific Literature |
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