| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2061901 | B | Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 mins by Amplite fluorimetric assay | Homo sapiens | 59 | cell-based format | Scientific Literature | ||
| 2. | ALA2061902 | B | Inhibition of G6PD in HEK293T cells assessed as accumulation of 6-phosphogluconate after 5 hrs by LC-MS/MS analysis using 6-aminonicotinamide | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA2061903 | B | Ratio of IC50 for G6PD in HEK293T cells to IC50 for human recombinant G6PD expressed in Escherichia coli JM109 (DE3) cells | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA1011499 | B | Inhibition of human G6PDH using glucose-6-phosphate as substrate by Lineweaver-Burke plot | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA1011500 | B | Inhibition of human G6PDH using NADP as substrate by Lineweaver-Burke plot | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA1737961 | F | PUBCHEM_BIOASSAY: Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] | 587 | assay format | PubChem BioAssays | |||
| 7. | ALA2174116 | B | Inhibition of human glucose-6-phosphate dehydrogenase after 90 mins by resazurin/diaphorasecoupled assay | Homo sapiens | 44 | single protein format | Scientific Literature | ||
| 8. | ALA4147382 | B | Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 9. | ALA4147386 | B | Competitive inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by Lineweaver-Burk plot analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 10. | ALA4256255 | B | Inhibition of glucose-6-phosphate dehydrogenase (unknown origin) at 100 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4630207 | A | Inhibition of recombinant human G6PDH expressed in Escherichia coli by fluorescence assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 12. | ALA4630209 | A | Inhibition of recombinant human G6PDH expressed in Escherichia coli at 80 uM by fluorescence assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4681698 | B | Inhibition of wild type G6PD (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4816197 | B | Non-competitive inhibition of G6PD (unknown origin) using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4816198 | B | Binding affinity to G6PD (unknown origin) assessed as equilibrium dissociation constant by surface plasmon resonance assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4816199 | B | Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+ as substrate incubated for 15 mins by UV absorption photometry assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 17. | ALA4816200 | B | Non-competitive inhibition of G6PD (unknown origin) assessed as Km at 2.2 to 11.1 uM using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4816201 | B | Competitive inhibition of G6PD (unknown origin) using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA4816202 | B | Competitive inhibition of G6PD (unknown origin) assessed as Km at 2.2 to 11.1 uM using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4816203 | B | Non-competitive inhibition of G6PD (unknown origin) assessed as Vmax at 2.2 to 11.1 uM using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten analysis | Homo sapiens | 1 | single protein format | Scientific Literature |
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