| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA906588 | B | Inhibition of Bacillus anthracis protective antigen 63 reconstituted in diphytanoylphosphatidylcholine lipid membranes assessed as inhibition of channel conductance at 5 uM | Bacillus anthracis | 1 | assay format | Scientific Literature | ||
| 2. | ALA956382 | B | Inhibition of Bacillus anthracis protective antigen binding to cell surface of mouse RAW264.7 cells at 12.5 uM after 2 hrs by flow cytometry | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA956383 | B | Inhibition of Bacillus anthracis protective antigen pore formation in mouse RAW264.7 cells at 12.5 uM after 2 hrs | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA1049444 | B | Inhibition of Bacillus anthracis anthrax protective antigen heptamer pre-pore to pore conversion in CMG2-expressing CHO cells | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA1049445 | B | Inhibition of Bacillus anthracis anthrax protective antigen heptamer pre-pore to pore conversion in TEM8-expressing CHO cell | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA1049446 | B | Inhibition of Bacillus anthracis anthrax protective antigen binding to CMG2 expressing CHO cells | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA1049447 | B | Inhibition of Bacillus anthracis anthrax protective antigen binding to TEM8-expressing CHO cells | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA1049448 | B | Inhibition of Bacillus anthracis anthrax proteolytic protective antigen processing in CMG2 expressing CHO cells | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA1049449 | B | Inhibition of Bacillus anthracis anthrax proteolytic protective antigen processing in TEM2 expressing CHO cells | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA1049450 | B | Inhibition of heptamerization of Bacillus anthracis anthrax protective antigen in CMG2 expressing CHO cells | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA1049451 | B | Inhibition of heptamerization of Bacillus anthracis anthrax protective antigen in TEM2 expressing CHO cells | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA1049452 | B | Inhibition of Bacillus anthracis anthrax protective antigen-dependent lethal factor binding in CMG2 expressing CHO cells | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA1049453 | B | Inhibition of Bacillus anthracis anthrax protective antigen-dependent lethal factor binding in TEM2 expressing CHO cells | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA2185584 | B | Inhibition of Bacillus anthracis Protective antigen assessed as reduction in SDS-resistant oligomer level in CHO C4 cells at 100 uM after 1 hr by Western blot analysis relative to untreated-control in presence of lethal factor | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA2185586 | B | Inhibition of Bacillus anthracis Protective antigen assessed as reduction in PA83 level in CHO C4 cells at 100 uM after 1 hr by Western blot analysis relative to untreated-control in presence of lethal factor | Bacillus anthracis | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA2185591 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells at 3 uM compound co-treated for 5 hrs with antigen measured after 48 hrs by MTT assay in presence of FP59 | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA2185592 | B | Inhibition of matrix metalloprotease activated Bacillus anthracis Protective antigen-mediated cytotoxicity in HT1080 cells at 100 uM compound co-treated for 5 hrs with antigen measured after 48 hrs by MTT assay in presence of FP59 | Bacillus anthracis | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA2185593 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in HT1080 cells at 100 uM compound co-treated for 5 hrs with antigen measured after 48 hrs by MTT assay in presence of FP59 | Bacillus anthracis | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA2185594 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells at 100 uM compound co-treated for 5 hrs with antigen measured after 48 hrs by MTT assay in presence of FP59 | Bacillus anthracis | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA2185595 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells at 100 uM compound co-treated for 5 hrs with antigen by MTT assay in presence of lethal factor | Bacillus anthracis | 1 | cell-based format | Scientific Literature |
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