| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1832655 | B | Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysis | Mus musculus | 16 | single protein format | Scientific Literature | ||
| 2. | ALA1832672 | B | Inhibition of mouse STAT3 SH2 domain using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 30 mins by fluorescence polarisation assay | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 3. | ALA1005389 | B | Displacement of pTyr705 from flag-tagged mouse Stat3 SH2 domain expressed in HEK293 cells up to 200 uM by fluorescence polarization | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1006358 | B | Inhibition of STAT3 phosphorylation in mouse Ba/F3 NPM-ALK cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1006363 | B | Inhibition of STAT3 in mouse Ba/F3 NPM-ALK cells at 50 nM | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1657357 | B | Binding affinity to mouse Stat3 by surface plasmon resonance assay | Mus musculus | 46 | single protein format | Scientific Literature | ||
| 7. | ALA1657358 | B | Inhibition of mouse Stat3 DNA binding activity by EMSA | Mus musculus | 46 | single protein format | Scientific Literature | ||
| 8. | ALA1657365 | B | Inhibition of constitutive Stat3 Y705 phosphorylation in v-Src transformed mouse NIH/3T3 cells at 40 or 50 uM after 12 to 48 hrs by immunoblotting | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA1657369 | B | Inhibition of constitutive Stat3 Y705 phosphorylation in v-Src transformed mouse NIH/3T3 cells at 40 uM after 15 to 60 mins by immunoblotting | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA1657521 | B | Inhibition of EGF-srimulated Stat3 Y705 phosphorylation in mouse NIH/3T3 cells overexpressing human EGFR at 40 uM after 15 to 60 mins by immunoblotting | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA1687311 | B | Inhibition of STAT3 dimerization in v-Src transformed mouse NIH3T3 cells assessed as suppression of STAT3-DNA binding activity in nucleus at 100 uM after 24 hrs by electrophoretic mobility shift assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA1687312 | B | Inhibition of STAT3 dimerization in v-Src transformed mouse NIH3T3 cells assessed as suppression of STAT3-DNA binding activity in nucleus at 100 uM after 6 hrs by electrophoretic mobility shift assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA1687314 | B | Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Mus musculus | 12 | assay format | Scientific Literature | ||
| 14. | ALA1687315 | B | Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 mins by electrophoretic mobility shift assay | Mus musculus | 14 | cell-based format | Scientific Literature | ||
| 15. | ALA1687318 | B | Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assay | Mus musculus | 5 | single protein format | Scientific Literature | ||
| 16. | ALA2175185 | B | Binding affinity to STAT3 SH2 in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA2175187 | B | Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction in nucleus after 30 mins by EMSA | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 18. | ALA2175196 | B | Inhibition of STAT3 dimerization in EGF-stimulated mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction after 30 mins by EMSA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3630526 | B | Inhibition of STAT3 in Oncostatin M induced mouse B9 cells assessed as decrease of phospho-STAT3 in nucleus in presence of IL-6 by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3630527 | B | Inhibition of STAT3 in Oncostatin M induced mouse B9 cells assessed as accumulation of STAT3 in cytoplasm in presence of IL-6 by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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