# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3636207 | Binding | Inhibition of PRMT4 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assay | Homo sapiens | 1 | ALA3632463 | single protein format | Scientific Literature | |
2. | ALA3784076 | Binding | Inhibition of GST-tagged CARM1 (unknown origin) using tritiated S-adenosylmethionine as substrate at 6 nM by methylation- based filter assay | Homo sapiens | 2 | ALA3779843 | single protein format | Scientific Literature | |
3. | ALA3784077 | Binding | Inhibition of CARM1 (unknown origin) using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity assay | Homo sapiens | 5 | ALA3779843 | single protein format | Scientific Literature | |
4. | ALA3784629 | Binding | Inhibition of human PRMT4 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity assay | Homo sapiens | 4 | ALA3779843 | single protein format | Scientific Literature | |
5. | ALA1804363 | Binding | Inhibition of CARM1-mediated methylation of PABP1 at 20 uM after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine | 5 | ALA1799916 | single protein format | Scientific Literature | ||
6. | ALA1804593 | Binding | Inhibition of CARM1-mediated methylation of PABP1 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine | 10 | ALA1799916 | single protein format | Scientific Literature | ||
7. | ALA1804747 | Binding | Inhibition of CARM1-mediated methylation of PABP1 at 100 uM after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine | 3 | ALA1799916 | single protein format | Scientific Literature | ||
8. | ALA1804748 | Binding | Inhibition of CARM1-mediated methylation of CA150 at 100 uM after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine | 3 | ALA1799916 | single protein format | Scientific Literature | ||
9. | ALA1804749 | Binding | Inhibition of CARM1-mediated methylation of SMB at 100 uM after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine | 3 | ALA1799916 | single protein format | Scientific Literature | ||
10. | ALA1804750 | Binding | Inhibition of CARM1-mediated methylation of histone H3 at 100 uM after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine | 3 | ALA1799916 | single protein format | Scientific Literature | ||
11. | ALA1804758 | Binding | Inhibition of CARM1 expressed in tetracycline-induced human HEK293 cells coexpressing flag-tagged PABP1 assessed as inhibition of PABP1 methylation at 1 to 5 uM by SDS-PAGE analysis | 1 | ALA1799916 | cell-based format | Scientific Literature | ||
12. | ALA1804759 | Binding | Inhibition of CARM1-mediated prostate specific antigen promoter activity in human LNCAP cells after 48 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA1799916 | cell-based format | Scientific Literature | |
13. | ALA1804760 | Binding | Inhibition of CARM1-mediated prostate specific antigen promoter activity in human LNCAP cells at 30 uM after 48 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA1799916 | cell-based format | Scientific Literature | |
14. | ALA3411811 | Binding | Displacement of [3H]-SAM from recombinant His6-tagged CARM1 (unknown origin) expressed in Escherichia coli BL21(DE3) incubated for 5 mins prior to H4(1 to 20)-BTN peptide addition measured after 8 mins by scintillation proximity assay | Homo sapiens | 3 | ALA3407369 | assay format | Scientific Literature | |
15. | ALA3420961 | Binding | Inhibition of human CARM1 (19 to 608) using histamine H3 (1 to 40) as substrate assessed as transfer of [3H]-Me of [3H-Me]-SAM to peptide substrate after 7 hrs by scintillation counting analysis | Homo sapiens | 1 | ALA3414551 | single protein format | Scientific Literature | |
16. | ALA3421221 | Binding | Competitive inhibition of human CARM1 using oligo-nucleosome as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins in presence of SAM | Homo sapiens | 1 | ALA3414551 | single protein format | Scientific Literature | |
17. | ALA3421465 | Binding | Inhibition of recombinant human GST-tagged CARM1 | Homo sapiens | 1 | ALA3414551 | single protein format | Scientific Literature | |
18. | ALA3421490 | Binding | Inhibition of CARM1 in human HeLa cells assessed as reduction of H3R17 methylation at 5 uM after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA3414551 | cell-based format | Scientific Literature | |
19. | ALA1037272 | Binding | Inhibition of human CARM1 assessed as inhibition of histone3 methylation | Homo sapiens | 13 | ALA1155316 | single protein format | Scientific Literature | |
20. | ALA1037273 | Binding | Inhibition of human CARM1 assessed as inhibition of HuR methylation | Homo sapiens | 1 | ALA1155316 | single protein format | Scientific Literature |