# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA981770 | B | Inhibition of SgK085 at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
2. | ALA1051352 | B | Binding constant for SgK085 kinase domain | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
3. | ALA1052963 | B | Inhibition of SgK085 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
4. | ALA1167698 | B | Inhibition of SgK085 at 1 uM | 6 | ALA1165965 | single protein format | Scientific Literature | ||
5. | ALA1174934 | B | Inhibition of MYLK4 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
6. | ALA1244976 | B | Binding affinity to SgK085 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
7. | ALA1679284 | B | Binding affinity to MYLK4 at 10 uM by immobilized ligand displacement assay | 1 | ALA1671850 | single protein format | Scientific Literature | ||
8. | ALA1826701 | B | Activity of SgK085 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
9. | ALA1908506 | B | Binding constant for MYLK4 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
10. | ALA1936979 | B | Inhibition of MYLK4 at 10 uM after 1 hr by competitive binding assay | 1 | ALA1933013 | single protein format | Scientific Literature | ||
11. | ALA1947282 | B | Binding affinity to SGK085 assessed as change in thermal denaturation at 10 uM by thermal stability shift assay | 17 | ALA1944596 | single protein format | Scientific Literature | ||
12. | ALA2215440 | B | Inhibition of MYLK4 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
13. | ALA2215618 | B | Binding affinity to T7-phage-tagged SgK085 by PCR analysis | 1 | ALA2203077 | single protein format | Scientific Literature | ||
14. | ALA2394161 | B | Competitive binding affinity to MYLK4 (unknown origin) assessed as enzyme remaining bound to anchored active-site ligand at 10 uM relative to control | Homo sapiens | 1 | ALA2390846 | single protein format | Scientific Literature | |
15. | ALA2428993 | B | Competitive binding affinity to SgK085 (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 4 | ALA2424622 | single protein format | Scientific Literature | |
16. | ALA2429168 | B | Binding affinity to SgK085 (unknown origin) | Homo sapiens | 1 | ALA2424622 | single protein format | Scientific Literature | |
17. | ALA3812027 | B | Inhibition of human MYLK4 assessed as remaining enzyme activity at 1 uM by KINOMEscan assay | Homo sapiens | 1 | ALA3808325 | single protein format | Scientific Literature | |
18. | ALA4025263 | B | Inhibition of wild-type human partial length MYLK4 (V79 to S380 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
19. | ALA4044074 | B | Inhibition of wild-type human partial length MYLK4 (V79 to S380 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | assay format | Scientific Literature | |
20. | ALA4055044 | B | Inhibition of wild-type human partial length SGK085 (V79 to S380 residues) expressed in bacterial expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4052645 | assay format | Scientific Literature |